Based on the results previously reported, several phenazine derivatives containing an alkylating group were synthesized. Antitumor activity of these substances was screened with Ehrlich ascites carcinoma, in ascites and solid form. The results are shown in Tables I and II and in Figs. 1, 2-1, 2-2. Compounds VIII and XIII showed an activity comparable to that of 6-Mercaptopurine in ascites form in a dose of 50γ/mouse/day.
