Convallasaponin A, a New 5β-Spirostanol Triglycoside from the Rhizomes of Convallaria majalis

Taro Higano; Minpei Kuroda; Hiroshi Sakagami; Yoshihiro Mimaki

doi:10.1248/cpb.55.337

Notes

Convallasaponin A, a New 5β-Spirostanol Triglycoside from the Rhizomes of Convallaria majalis

Taro Higano, Minpei Kuroda, Hiroshi Sakagami, Yoshihiro Mimaki

Author information

Keywords: Convallaria majalis L., Liliaceae, 5β-spirostanol triglycoside, convallasaponin A, cardenolide glycoside, cytotoxic activity

JOURNAL FREE ACCESS

2007 Volume 55 Issue 2 Pages 337-339

DOI https://doi.org/10.1248/cpb.55.337

Details

Abstract

The rhizomes of Convallaria majalis have been analyzed for their steroidal glycoside constituents, resulting in the isolation of a new 5β-spirostanol triglycoside, named convallasaponin A, along with two known cardenolide glycosides and a known cholestane glycoside. The structure of convallasaponin A was determined on the basis of extensive spectroscopic analysis, including 2D NMR data, and the results of hydrolytic cleavage. The cardenolide glycosides showed tumor specific cytotoxic activity.

Corresponding author

Register with J-STAGE for free!