A Novel Antivirally Active Fucan Sulfate Derived from an Edible Brown Alga, Sargassum horneri

Srisomporn PREEPRAME; Kyoko HAYASHI; Jung-Bum LEE; Ushio SANKAWA; Toshimitsu HAYASHI

doi:10.1248/cpb.49.484

Notes

A Novel Antivirally Active Fucan Sulfate Derived from an Edible Brown Alga, Sargassum horneri

Srisomporn PREEPRAME, Kyoko HAYASHI, Jung-Bum LEE, Ushio SANKAWA, Toshimitsu HAYASHI

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Keywords: fucan sulfate, antiviral activity, Sargassum horneri, brown alga, sulfated polysaccharide

JOURNAL FREE ACCESS

2001 Volume 49 Issue 4 Pages 484-485

DOI https://doi.org/10.1248/cpb.49.484

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Abstract

A novel fucan sulfate (Hor-1) was isolated from the hot water extract of an edible brown alga, Sargassum horneri (Turner) C. AGARDH. The fucan sulfate was revealed to have sugar linkage types, sulfate content and uronic acid content different from those of sodium hornan (Na-HOR), another fucan sulfate isolated from this alga. However, it exhibited inhibitory activity against replication of herpes simplex virus type 1 with similar potency to Na-HOR.

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