2000 Volume 48 Issue 9 Pages 1391-1394
Palladium catalyzed cross coupling reactions of a vinyl triflate intermediate and various alkenyl stananes afforded trisubstituted Z-olefins stereoselectively in high yields. These olefins were then converted to the corresponding 9Z-retinoic acids via Horner-Emmons reaction and subsequent basic hydrolysis in excellent yields.