Diterpene Glycosides from Leaves of Chinese Rubus chingii and Fruits of R. suavissimus, and Identification of the Source Plant of the Chinese Folk Medicine “Fu-pen-zi”

WEN-HUA CHOU; TOSHIHIKO OINAKA; FUJIKO KANAMARU; KENJI MIZUTANI; FENG-HUAI CHEN; OSAMU TANAKA

doi:10.1248/cpb.35.3021

Diterpene Glycosides from Leaves of Chinese Rubus chingii and Fruits of R. suavissimus, and Identification of the Source Plant of the Chinese Folk Medicine “Fu-pen-zi”

WEN-HUA CHOU, TOSHIHIKO OINAKA, FUJIKO KANAMARU, KENJI MIZUTANI, FENG-HUAI CHEN, OSAMU TANAKA

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Keywords: Rubus chingii, Rubus suavissimus, Rosaceae, Chinese folk medicine, fu-pen-zi, rubusoside, sweetener, goshonoside, diterpene glycoside, chemotaxonomy

JOURNAL FREE ACCESS

1987 Volume 35 Issue 7 Pages 3021-3024

DOI https://doi.org/10.1248/cpb.35.3021

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Abstract

Five diterpene glycosides, goshonoside-F1, -F2, -F3, -F4 and-F5 (4-8), which are characteristic of the leaves of Japanese R. chingii (Gosho-ichigo), were isolated from the leaves of Chinese R. chingii (Zhan-yei fu-pen-zi). This proved the chemotaxonomical identity of the plants. Compound 8 was also detected in commercial Chinese folk medicine, Fu-pen-zi, indicating that the source plant of this drug is R. chingii. Rubusoside (1), which is the sweet diterpene glycoside of the leaves of R. suavissimus (Chinese name : Gan-yei xuen-gou-zi), was also identified in fruits of the plant.

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