Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Anticoccidials. I. Syntheses and Anticoccidial Activity of 2-Amino-5-aryl-1, 3, 4-oxadiazoles, 5-Alkoxy-3-aryl-1H-1, 2, 4-triazoles, and 3-Aryl-⊿2-1, 2, 4-triazolin-5-ones
MITSUHIKO MANOTAKUJI SEOTOSHIMI MATSUNOKINICHI IMAI
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1976 Volume 24 Issue 11 Pages 2871-2876

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Abstract

A series of 2-amino-5-aryl-1, 3, 4-oxadiazoles, 5-alkoxy-3-aryl-1H-1, 2, 4-triazoles, and 3-aryl-⊿2-1, 2, 4-triazolin-5-ones were prepared and their anticoccidial activity was tested. Among them, 5-(3, 4-dichlorophenyl)- and 5-(2, 4, 5-trichlorophenyl)-2-amino-1, 3, 4-oxadiazoles, 3-(3, 4-dichlorophenyl)- and 3-(2, 4-dichlorophenyl)-5-ethoxy-1H-1, 2, 4-triazoles, and 3-(4-bromophenyl)-, 3-(4-chlorophenyl)-, and 3-(2, 4-dichlorophenyl)-⊿2-1, 2, 4-triazolin-5-ones showed moderate anticoccidial activity.

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© The Pharmaceutical Society of Japan
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