2006 Volume 54 Issue 10 Pages 1421-1424
Two new iridoid glucosides, verbenabraside A (1) and verbenabraside B (2), were isolated from the aerial parts of Verbena brasiliensis VELL., along with six known iridoid glucosides, gelsemiol 3-O-β-D-glucoside (3), verbraside (4), 9-hydroxysemperoside (5), griselinoside (6), aralidioside (7), and 6α-hydroxyforsythide dimethyl ester (8), three known phenylethanoid glycosides, 2-phenylethyl O-β-D-xylopyranosyl-(1→2)-β-D-glucopyranoside (9), acteoside (10), and leucosceptoside A (11), two known lignan glucosides, dihydroxymethyl-bis(3,5-dimethoxy-4-hydroxyphenyl) tetrahydrofuran-9 (or 9′)-O-β-glucopyranoside (12) and (+)-lyoniresinol 3α-O-β-D-glucopyranoside (13), a known methyl salicylate glucoside, methyl 2-O-β-D-glucopyranosylbenzoate (14), and two known sterols, β-sitosterol 3-O-β-D-glucopyranoside (15) and β-sitosterol (16). Their chemical structures were determined on the basis of spectroscopic data. Compound 1 exhibited stronger scavenging effect on the stable free radical 1,1-diphenyl-2-picrylhydrazyl than that of α-tocopherol.