Special Collection of Papers: Reviews
Bromopyrrole Alkaloids from Okinawan Marine Sponges Agelas spp.
2016 Volume 64 Issue 7 Pages 691-694
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2016 Volume 64 Issue 7 Pages 691-694
In our continuing study for structurally and biogenetically interesting natural products from marine organisms, Okinawan marine sponges Agelas spp. were investigated, resulting in the isolation of 18 unique alkaloids including five dimeric bromopyrrole alkaloids (1–5), ten monomeric bromopyrrole alkaloids (6–15), and three conjugates of monomeric bromopyrrole alkaloid and hydroxykynurenine (16–18). In this mini-review, the isolation, structure elucidation, and antimicrobial activities of these alkaloids are summarized.
