Skip to main content

Advertisement

SpringerLink
Log in

ASO Author Reflections: Impact of Glutathione Peroxidase 2 (GPX2) in Lung Adenocarcinoma

  • ASO Author Reflections
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Esworthy RS, Doroshow JH, Chu FF. The beginning of GPX2 and 30 years later. Free Radic Biol Med. 2022;188:419–33.

    Article  PubMed  PubMed Central  CAS  MATH  Google Scholar 

  2. Hashinokuchi A, Matsubara T, Ono Y, et al. Clinical and prognostic significance of glutathione peroxidase 2 in lung adenocarcinoma. Ann Surg Oncol. 2024. https://doi.org/10.1245/s10434-024-15116-z.

    Article  PubMed  MATH  Google Scholar 

  3. Peng F, Xu Q, Jing X, et al. GPX2 promotes EMT and metastasis in non-small cell lung cancer by activating PI3K/AKT/mTOR/Snail signaling axis. FASEB Bioadv. 2023;5:233–50.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  4. Wang M, Chen X, Fu G, et al. Glutathione peroxidase 2 overexpression promotes malignant progression and cisplatin resistance of KRAS-mutated lung cancer cells. Oncol Rep. 2022;48:207.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  5. Ahmed KM, Veeramachaneni R, Deng D, et al. Glutathione peroxidase 2 is a metabolic driver of the tumor immune microenvironment and immune checkpoint inhibitor response. J Immunother Cancer. 2022;10:e004752.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

    Asato Hashinokuchi MD, Tomoyoshi Takenaka MD, PhD & Tomoharu Yoshizumi MD, PhD

  2. Department of Thoracic Surgery, Kitakyushu Municipal Medical Center, Kitakyushu, Fukuoka, Japan

    Taichi Matsubara MD, PhD

Authors
  1. Asato Hashinokuchi MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Taichi Matsubara MD, PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Tomoyoshi Takenaka MD, PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Tomoharu Yoshizumi MD, PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Taichi Matsubara MD, PhD.

Ethics declarations

Disclosure

The authors have no conflicts of interest.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This article refers to: Hashinokuchi, A, Matsubara, T, Ono Y, et al. Clinical and prognostic significance of glutathione peroxidase 2 in lung adenocarcinoma. Ann Surg Oncol. 2024. https://doi.org/10.1245/s10434-024-15116-z.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Hashinokuchi, A., Matsubara, T., Takenaka, T. et al. ASO Author Reflections: Impact of Glutathione Peroxidase 2 (GPX2) in Lung Adenocarcinoma. Ann Surg Oncol (2024). https://doi.org/10.1245/s10434-024-15177-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1245/s10434-024-15177-0

Search

Navigation