Skip to main content

Advertisement

SpringerLink
Log in

The WASH (Water or Saline at High Volumes) Trial: A Randomized Trial to Assess the Survival Impact of Extensive Peritoneal Lavage Using Distilled Water or Saline at High Volumes After Pancreatic Resection for Pancreatic Ductal Adenocarcinoma

  • ASO Research Letter
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Yamamoto K, Shimada S, Hirota M, Yagi Y, Matsuda M, Baba H. EIPL (extensive intraoperative peritoneal lavage) therapy significantly reduces peritoneal recurrence after pancreatectomy in patients with pancreatic cancer. Int J Oncol. 2005;27(5):1321–8.

    PubMed  Google Scholar 

  2. Lee SR, Kim HO, Son BH, Yoo CH, Shin JH. Prognostic factors associated with long-term survival and recurrence in pancreatic adenocarcinoma. Hepato-gastroenterology Mar-Apr. 2013;60(122):358–62.

    CAS  Google Scholar 

  3. Steen MW, van Duijvenbode DC, Dijk F, et al. Tumor manipulation during pancreatic resection for pancreatic cancer induces dissemination of tumor cells into the peritoneal cavity: a systematic review. HPB. 2018;20(4):289–96.

    Article  Google Scholar 

  4. Hirota M, Shimada S, Yamamoto K, et al. Pancreatectomy using the no-touch isolation technique followed by extensive intraoperative peritoneal lavage to prevent cancer cell dissemination: a pilot study. J Pancreas. 2005;6(2):143–51.

    Google Scholar 

  5. Papai E, Nevler A, Solomides C, et al. Intraoperative cytologic sampling for resected pancreatic and periampullary adenocarcinoma with implications for locoregional recurrence-free survival. J Am Coll Surg. 2022;234(1):48–53.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Surgical Oncology Program, Center for Cancer Research, National Cancer Institute, NationalInstitutesofHealth, Bethesda, MD, USA

    Areeba Saif MD, Martha Teke MD, Carrie Ryan MD & Jonathan M. Hernandez MD

  2. Section of Hepatopancreatobiliary Surgery, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA

    Emily Papai MD, Avinoam Nevler MD & Harish Lavu MD

Authors
  1. Areeba Saif MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Martha Teke MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Carrie Ryan MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Emily Papai MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Avinoam Nevler MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Jonathan M. Hernandez MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Harish Lavu MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Jonathan M. Hernandez MD or Harish Lavu MD.

Ethics declarations

Disclosure

The authors declare that they have no conflict of interest.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file1 (DOCX 161 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Saif, A., Teke, M., Ryan, C. et al. The WASH (Water or Saline at High Volumes) Trial: A Randomized Trial to Assess the Survival Impact of Extensive Peritoneal Lavage Using Distilled Water or Saline at High Volumes After Pancreatic Resection for Pancreatic Ductal Adenocarcinoma. Ann Surg Oncol 29, 5372–5374 (2022). https://doi.org/10.1245/s10434-022-11978-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1245/s10434-022-11978-3

Search

Navigation