References
Sasaki T, Isayama H, Nakai Y, et al. A retrospective study of gemcitabine and cisplatin combination therapy as second-line treatment for advanced biliary tract cancer. Chemotherapy. 2013;59(2):106–11.
Chang TY, Chang CC, Cheng D. Acyl-coenzyme A: cholesterol acyltransferase. Ann Rev Biochem. 1997;66:613–38.
Li J, Qu X, Tian J, Zhang JT, Cheng JX. Cholesterol esterification inhibition and gemcitabine synergistically suppress pancreatic ductal adenocarcinoma proliferation. PloS One. 2018;13(2):e0193318.
Ueno G, Iwagami Y, Kobayashi S. ACAT-1-regulated cholesteryl ester accumulation modulates gemcitabine resistance in biliary tract cancer. Ann Surg Oncol. 2021. https://doi.org/10.1245/s10434-021-11152-1.
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Goro Ueno, Yoshifumi Iwagami, Shogo Kobayashi, Suguru Mitsufuji, Daisaku Yamada, Yoshito Tomimaru, Hirofumi Akita, Tadafumi Asaoka, Takehiro Noda, Kunihito Gotoh, Masaki Mori, Yuichiro Doki, and Hidetoshi Eguchi have no conflicts of interest to report.
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Ueno, G., Iwagami, Y., Kobayashi, S. et al. ASO Author Reflections: ACAT-1-Regulated Cholesteryl Ester Accumulation Modulates Gemcitabine Resistance in Biliary Tract Cancer. Ann Surg Oncol 29, 2910–2911 (2022). https://doi.org/10.1245/s10434-021-11162-z
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DOI: https://doi.org/10.1245/s10434-021-11162-z