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Implications of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) for Breast Cancer Reconstruction: An Update for Surgical Oncologists

  • Reconstructive Oncology
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

Abstract

Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare disease that has been diagnosed in an extremely small proportion of women with breast implants. The pathogenesis of this disease is currently poorly understood, but it appears to be related to textured implants. Recent high-profile media coverage of this rare clinical entity is likely to cause considerable anxiety for breast cancer patients who have undergone alloplastic breast reconstruction. The purpose of this review is to provide surgical oncologists with an evidence-based overview of the incidence, diagnosis, and management of BIA-ALCL with a particular emphasis on breast reconstruction cases. It is essential that surgical oncologists are familiar with BIA-ALCL, because although it is extremely rare, early recognition and surgical resection will be curative in many cases.

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Authors and Affiliations

  1. Division of Plastic and Reconstructive Surgery, Department of Surgical Oncology, University Health Network, Toronto, Canada

    Anne C. O’Neill MBBCh, PhD, Toni Zhong MD, MHS & Stefan O. P. Hofer MD, PhD

  2. Department of Surgery, University of Toronto, Toronto, Canada

    Anne C. O’Neill MBBCh, PhD, Toni Zhong MD, MHS & Stefan O. P. Hofer MD, PhD

Authors
  1. Anne C. O’Neill MBBCh, PhD
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  2. Toni Zhong MD, MHS
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  3. Stefan O. P. Hofer MD, PhD
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Corresponding author

Correspondence to Anne C. O’Neill MBBCh, PhD.

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O’Neill, A.C., Zhong, T. & Hofer, S.O.P. Implications of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) for Breast Cancer Reconstruction: An Update for Surgical Oncologists. Ann Surg Oncol 24, 3174–3179 (2017). https://doi.org/10.1245/s10434-017-6014-0

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  • DOI: https://doi.org/10.1245/s10434-017-6014-0

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