Skip to main content
SpringerLink
Log in

Local Excision for Rectal Cancer—Safety and Efficacy Challenges

  • Gastrointestinal Oncology
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Enker WE, Thaler HT, Cranor ML, Polyak T. Total mesorectal excision in the operative treatment of carcinoma of the rectum. J Am Coll Surg. 1995;181:335–46.

    PubMed  CAS  Google Scholar 

  2. Roukos DH. Adjuvant chemoradiotherapy in gastric cancer: wave goodbye to extensive surgery? Ann Surg Oncol. 2002;9:220–1.

    Article  PubMed  Google Scholar 

  3. Roukos DH. Personalized cancer diagnostics and therapeutics. Expert Rev Mol Diagn. 2009;9:227–9.

    Article  PubMed  Google Scholar 

  4. Borschitz T, Gockel I, Kiesslich R, Junginger T. Oncological outcome after local excision of rectal carcinomas. Ann Surg Oncol. 2008;15:3101–8.

    Article  PubMed  Google Scholar 

  5. Baik SH, Lee WJ, Rha KH, Kim NK, Sohn SK, Chi HS, et al. Robotic total mesorectal excision for rectal cancer using four robotic arms. Surg Endosc. 2008;22(3):792–7.

    Article  PubMed  Google Scholar 

  6. Liakakos T, Roukos DH. More controversy than ever—challenges and promises towards personalized treatment of gastric cancer. Ann Surg Oncol. 2008;15(4):956–60.

    Article  PubMed  Google Scholar 

  7. Roukos DH, Kappas AM, Agnantis NJ. Perspectives and risks of breast-conservation therapy for breast cancer. Ann Surg Oncol. 2003;10:718–21.

    Article  PubMed  Google Scholar 

  8. Fatouros M, Roukos DH, Arampatzis I, Sotiriadis A, Paraskevaidis E, Kappas AM. Factors increasing local recurrence in breast-conserving surgery. Expert Rev Anticancer Ther. 2005;5(4):737–45.

    Article  PubMed  Google Scholar 

  9. Roukos DH, Lykoudis E, Liakakos T. Genomics and challenges toward personalized breast cancer local control. J Clin Oncol. 2008;26(26):4360–1.

    Article  PubMed  Google Scholar 

  10. Briasoulis E, Fatouros M, Roukos DH. Level I evidence in support of perioperative chemotherapy for operable gastric cancer: sufficient for wide clinical use? Ann Surg Oncol. 2007;14:2691–5.

    Article  PubMed  Google Scholar 

  11. Roukos DH. Linking contralateral breast cancer with genetics. Radiother Oncol. 2008;86:139–41.

    Article  PubMed  Google Scholar 

  12. Briasoulis E, Liakakos T, Dova L, Fatouros M, Tsekeris P, Roukos DH, et al. Selecting a specific pre- or postoperative adjuvant therapy for individual patients with operable gastric cancer. Expert Rev Anticancer Ther. 2006;6:931–9.

    Article  PubMed  Google Scholar 

  13. Roukos DH. Genetics and genome-wide association studies: surgery-guided algorithm and promise for future breast cancer personalized surgery. Expert Rev Mol Diagn. 2008;8(5):587–97.

    Article  PubMed  Google Scholar 

  14. Roukos DH. Innovative genomic-based model for personalized treatment of gastric cancer: integrating current standards and new technologies. Expert Rev Mol Diagn. 2008;8(1):29–39.

    Article  PubMed  CAS  Google Scholar 

  15. Roukos DH, Briasoulis E. Individualized preventive and therapeutic management of hereditary breast ovarian cancer. Nat Clin Pract Oncol. 2007;4(10):578–90.

    Article  PubMed  CAS  Google Scholar 

  16. Roukos DH. Personal genomics and genome-wide association studies: Novel discoveries but limitations for practical personalized medicine. Ann Surg Oncol. 2000;16:772–3.

    Article  Google Scholar 

  17. Fatouros M, Baltogiannis G, Roukos DH. The predominant role of surgery in the prevention and new trends in the surgical treatment of women with BRCA1/2 mutations. Ann Surg Oncol. 2008;15(1):21–33.

    Article  PubMed  Google Scholar 

  18. Roukos DH, Agnanti NJ, Paraskevaidis E, Kappas AM. Approaching the dilemma between prophylactic bilateral mastectomy or oophorectomy for breast and ovarian cancer prevention in carriers of BRCA1 or BRCA2 mutations. Ann Surg Oncol. 2002;9(10):941–3.

    PubMed  Google Scholar 

  19. Agnantis NJ, Paraskevaidis E, Roukos D. Preventing breast, ovarian cancer in BRCA carriers: rational of prophylactic surgery and promises of surveillance. Ann Surg Oncol. 2004;11(12):1030–4.

    Article  PubMed  Google Scholar 

  20. Roukos DH. Prognosis of breast cancer in carriers of BRCA1 and BRCA2 mutations. N Engl J Med. 2007;357(15):1555–6; author reply 1556.

    Article  PubMed  CAS  Google Scholar 

  21. Ziogas D, Baltogiannis G, Fatouros M, Roukos DH. Identifying and preventing high-risk gastric cancer individuals with CDH1 mutations. Ann Surg. 2008;247(4):714–5.

    Article  PubMed  Google Scholar 

  22. Roukos DH. HER2 and response to paclitaxel in node-positive breast cancer. N Engl J Med. 2008;358:197, author reply 198.

    Article  PubMed  CAS  Google Scholar 

  23. Roukos DH. Breast-cancer stromal cells with TP53 mutations. N Engl J Med. 2008;358(15):1636; author reply 1636.

    PubMed  CAS  Google Scholar 

  24. Roukos DH. Mea Culpa with cancer-targeted therapy: new thinking and new agents design for novel, causal networks-based, personalized biomedicine. Expert Rev Mol Diagn. 2009;9(3):217–21.

    Article  PubMed  Google Scholar 

  25. Roukos DH. Genome-wide association studies: how predictable is a person's cancer risk? Expert Rev Anticancer Ther. 2009;9(4):389–92.

    Article  PubMed  Google Scholar 

  26. Roukos DH. Radiation therapy for breast cancer. N Engl J Med. 2009;360(13):1362–3.

    Article  PubMed  CAS  Google Scholar 

  27. Roukos DH. Twenty-one-gene assay: challenges and promises in translating personal genomics and whole-genome scans into personalized treatment of breast cancer. J Clin Oncol. 2009;27(8):1337–8.

    Article  PubMed  Google Scholar 

  28. Roukos DH. Assessing both genetic variation (SNPs/CNVs) and gene-environment interactions may lead to personalized gastric cancer prevention. Expert Rev Mol Diagn. 2009;9(1):1–6.

    Article  PubMed  CAS  Google Scholar 

  29. Roukos DH. Genome-wide association studies and aggressive surgery toward individualized prevention, and improved local control and overall survival for gastric cancer. Ann Surg Oncol. 2009;16(4):795–8.

    Article  PubMed  Google Scholar 

  30. Kappas AM, Roukos DH. Quality of surgery determinant for the outcome of patient with gastric cancer. Ann Surg Oncol. 2002;9:828–30.

    Article  PubMed  Google Scholar 

  31. Roukos DH, Paraschou P, Lorenz M. Distal gastric cancer and extensive surgery: a new evaluation method based on the study of the status of residual lymph nodes after limited surgery. Ann Surg Oncol. 2000;7(10):719–26.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Second Propedeutical Department of Surgery, Aristotle University of Thessaloniki, Thessaloniki, Greece

    G. Marakis MD

  2. 4th Surgical Department, Aristotle University of Thessaloniki, Thessaloniki, Greece

    H. Demetriades MD & I. Kanellos MD

  3. Department of Surgery, Ioannina University School of Medicine, Ionnina, Greece

    D. Ziogas MD

Authors
  1. G. Marakis MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. Demetriades MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. D. Ziogas MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. I. Kanellos MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to D. Ziogas MD.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Marakis, G., Demetriades, H., Ziogas, D. et al. Local Excision for Rectal Cancer—Safety and Efficacy Challenges. Ann Surg Oncol 16, 2369–2370 (2009). https://doi.org/10.1245/s10434-009-0499-0

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1245/s10434-009-0499-0

Keywords

Search

Navigation