ABSTRACT
Entering the 21st century, scientific frontiers have moved to a
new horizon toward understanding the entire biological systems.
Revealing the enzymes’ functions on the basis of their primary
sequences and substrate structures is a new approach to reach this
mega goal. It presents a great opportunity and also an unparalleled
challenge due to the vast volume of data. Biocatalysis has supplied
seminal knowledge. On the foundation of this, combining the
use of databases created of experimental data of enzyme activity
and computational methods such as molecular modeling and
bioinformatics tool makes it possible to establish the relationship
between enzymes’ primary sequences and their catalytic functions.
In this chapter, a discussion is provided and a model is proposed on
the basis of review of amassed literatures and distilled information,
with emphasis on the potentially useful technologies.