Journal of Lipid Research
Research ArticlesBRCA1 is a novel regulator of metabolic function in skeletal muscle
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This work was funded by National Institutes of Health Grant AR059913 (E.E.S.), an ACSM student doctoral grant (K.C.J.), and a KNES GRIF fund grant (K.C.J.). K.C.J. was supported by National Institutes of Health Grant AG000268. J.N. was supported by the Swedish National Centre for Research in Sports. R.A.S. was supported by VA Research Service Rehabilitation R&D REAP and Biomedical R&D CDA02.
Abbreviations:
- ACC
acetyl-CoA carboxylase
- ACC-p
phosphorylated form of acetyl-CoA carboxylase
- AICAR
5-amino-1-β-D-ribofuranosyl-imidazole-4-carboxamide
- AMPK
AMP-activated protein kinase
- BRCA1
Breast Cancer 1, early onset
- BRCA1 MG KO
mammary gland tissue from breast cancer type 1 KO mice
- BRCT
after the C_terminal domain of a breast cancer susceptibility protein
- CPT-1
carnitine palmitoyltransferase-1
- DCF
2′,7′-dichlorofluorescein
- HFD
high-fat diet
- MaCoA
malonyl-CoA
- 2-NBDG
2-[N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) amino]-2-deoxy-D-glucoseR
- NCD
normal chow diet
- OCR
oxygen consumption rate
- RFP
red fluorescent protein
- ROS
reactive oxygen species
- TA
tibialis anterior
- VL
vastus lateralis