Journal of Lipid Research
Volume 54, Issue 9, September 2013, Pages 2423-2436
Research ArticlesObese adipocytes show ultrastructural features of stressed cells and die of pyroptosis
Under a Creative Commons license
open access
adipose tissue
diabetes
obesity
electron microscopy
inflammation
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This work was supported by grants from Marche Polytechnic University (Contributi Ricerca Scientifica), the European Commission's Seventh Framework Programme for Research and Technological Development (EU FP7) project DIABAT (HEALTH-F2-2011-278373), and the Italian Ministry of University (PRIN 2010-11 to S.C.).
- CLS
crown-like structure
- FAT-ATTAC
fat apoptosis through targeted activation of caspase-8
- HFD
high-fat diet
- HOMA
Homeostasis Model Assessment
- HR-SEM
high-resolution scanning electron microscopy
- IL
interleukin
- NLRP3
nucleotide-binding oligomerization domain (NOD)-like receptor (NLR)-3
- RER
rough endoplasmic reticulum
- ROS
reactive oxygen species
- TEM
transmission electron microscopy
- TRXNIP
thioredoxin-interacting protein
- WAT
white adipose tissue
- WT
wild-type
Abbreviations
© 2013 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.