Hostname: page-component-8448b6f56d-qsmjn Total loading time: 0 Render date: 2024-04-24T04:15:40.131Z Has data issue: false hasContentIssue false

“Endogenous” and “Neurotic” Syndromes of Depression: A 5-to 7-Year Follow-up of 104 Cases

Published online by Cambridge University Press:  29 January 2018

D. W. K. Kay
Affiliation:
Royal Victoria Infirmary, and University of Newcastle upon Tyne
R. F. Garside
Affiliation:
University of Newcastle upon Tyne
J. R. Roy
Affiliation:
Newcastle Regional Hospital Board
Pamela Beamish
Affiliation:
St. Nicholas Hospital, Gosforth, Newcastle upon Tyne

Extract

In a previous paper (Kay et al., 1969) the mode of selection and composition of a sample of 104 depressed patients was described. The present article concerns the follow up of this sample, 5–7 years after the index admission (which was always a first admission). The aims were: (i) To examine and compare outcome in three groups of patients, “endogenous”, “neurotic”, and “undifferentiated”, (ii) The second aim was to study the power of various individual features to predict the course and outcome of the illness. The patients' groups were defined by the factor scores on a first (bipolar) factor which was identifiable in many though not all respects with the “endogenous-neurotic” factor previously described by Kiloh and Garside (1963) and by Carney, Roth and Garside (1965). A full account of the symptoms defining the factor, which was obtained by principal components analysis, and of the method of allocating patients to the diagnostic groupings, was given in the previous paper.

Type
Affective Disorders, Differentiation
Copyright
Copyright © Royal College of Psychiatrists, 1969 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Anderson, W. McC, and Dawson, J. (1962). “The clinical manifestations of depressive illness with abnormal acetyl methyl carbinol metabolism.” J. ment. Sci., 108, 8087.CrossRefGoogle Scholar
Anderson, W. McC, and Dawson, J. (1963). “Verbally retarded depression and sodium metabolism.” Brit. J. Psychiat., 109, 225230.CrossRefGoogle Scholar
Anderson, W. McC, (1968). “The isolation of primary affective illness.” Paper read at meeting of Northern and Midland Division, R.M.P.A., April, 1968.Google Scholar
Astrup, C, Fossum, A., and Holmboe, R. (1959). “A follow-up study of 270 patients with acute affective psychoses.” Acta psychiat. neurol. Scand., Supplement 135.Google Scholar
Board, F., Wadeson, R., and Persky, H. (1957). “Depressive affect and endocrine functions.” A.M.A. Arch. Neurol. Psychiat., 78, 612620.CrossRefGoogle Scholar
Carney, M. W. P., Roth, M., and Garside, R. F. (1965). “The diagnosis of depressive syndromes and the prediction of E.C.T. response.” Brit. J. Psychiat., 111, 659674.CrossRefGoogle Scholar
Colbert, J., and Harrow, M. (1967). “Psychomotor retardation in depressive syndromes.” J. new. ment. Dis., 145, 405419.CrossRefGoogle Scholar
Coppen, A. (1967). “The biochemistry of affective disorders.” Brit. J. Psychiat., 113, 12371264.CrossRefGoogle Scholar
Eberhard, G., Johnson, G., Nilsson, L., and Smith, G. J. W. (1965). “Clinical and experimental approaches to the description of depression and anti-depressive therapy.” Acta psychiat. neurol. Scand., Supplement 186.Google Scholar
Fawcett, J. A., and Bunney, W. E. J. (1967). “Pituitary-adrenal function and depression.” Arch. gen. Psychiat., 16, 517535.CrossRefGoogle Scholar
Greer, H. S., and Cawley, R. H. (1966). Natural History of Neurotic Illness. New South Wales: Australasia Medical Publishing Co.Google Scholar
Guilford, J. P. (1956). Fundamental Statistics in Psychology and Education. McGraw-Hill Book Company Inc.Google Scholar
Hamilton, M. (1960). “A rating scale for depression.” J. Neurol. Neurosurg. Psychiat., 23, 5662.CrossRefGoogle Scholar
Hamilton, M. (1967). “The development of a rating scale for depression.” Brit. J. soc. and clin. Psychol., 6, 278296.CrossRefGoogle Scholar
Hollister, L. E., Overall, J. E., Shelton, J., Pennington, V., Kinbell, I., and Johnson, M. (1967). “Drug therapy of depression.” Arch. gen. Psychiat., 17, 486493.CrossRefGoogle Scholar
Kay, D. W. K., Garside, R. F., Beamish, P., and Roy, J. R. (1969). “Endogenous and neurotic syndromes of depression: a factor analytical study of 104 cases. Clinical features.” Brit. J. Psychiat., 115, 377388.CrossRefGoogle Scholar
Kiloh, L. G., and Garside, R. F. (1963). “The independence of neurotic depression and endogenous depression.” Brit. J. Psychiat., 109, 451463.CrossRefGoogle Scholar
Lewis, Sir A. J. (1967). Inquiries in Psychiatry. London: Routledge.Google Scholar
Overall, J. E., Hollister, L. E., Johnson, M., and Pennington, V. (1966). “Nosology of depression and differentiated response to drugs.” J.A.M.A., 195, 946948.CrossRefGoogle Scholar
Pilowsky, I. (1967). “Dimensions of hypochondriasis.” Brit. J. Psychiat., 113, 8993.CrossRefGoogle Scholar
Rosenblatt, S., and Chanley, J. D. (1965). “Differences in the metabolism of norepinephrine in the depressions.” Arch. gen. Psychiat., 13, 495502.CrossRefGoogle Scholar
Rosenthal, S. H., and Gudeman, J. E. (1967). “The self-pitying constellation in depression.” Brit. J. Psychiat., 113, 485489.CrossRefGoogle Scholar
Strauss, E. B. (1960). In: Symposium on Depression. Royal College of Surgeons, London.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.