Abstract
Aims: to evaluate the outcomes of NTM pulmonary disease treatment in real life practice
Methods: retrospective study. All respiratory NTM isolations from 5 hospitals in northern Spain between 2012 and 2017 were analyzed. Microbiology, demographic data, radiologic features, treatment and outcome variables (cure, death, therapeutic failure) were collected
Results: 395 patients has at least one NTM isolation, 147 met 2007 ATS disease criteria and / or received treatment for NTM pulmonary disease. 34 patients did not receive treatment despite meeting ATS criteria. Main results are shown in the attached tables.
Multivariate analysis showed that only age> 75, the diagnosis of neoplasia and COPD were significant associated to all-cause mortality.
Conclusions: Mortality in patients with NTM pulmonary disease is high but mainly related to the underlying comorbidities of the patients.
Therapeutic failure is associated with the presence of M abcessus and bronchiectasis-nodular pattern in the CT scan.
Footnotes
Cite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 2798.
This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2020