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A measure of pupillary oscillation as a marker of cocaine-induced paranoia

Published Online:https://doi.org/10.1176/jnp.8.3.347

Cocaine-induced paranoia (CIP) remains an important drug-induced model of idiopathic paranoia for which no psychophysiologic marker has yet emerged. Measures of pupillary oscillation were able to significantly distinguish a group of abstinent crack cocaine abusers endorsing past CIP (n = 32) from another group of crack addicts who denied past CIP (n = 29).

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