Non-Enzymatic Glucose Sensor Based on Well-Crystallized ZnO Nanoparticles

In this paper, well-crystallized ZnO nanoparticles were rapidly synthesized by facile simple solution process at low temperature and used as an efficient electron mediator for the fabrication of non-enzymatic glucose sensor. The synthesized nanoparticles were characterized in terms of their morphological, structural and compositional properties. The detailed morphological characterizations confirmed the large-scale synthesis of well-crystalline wurtzite hexagonal phase ZnO nanoparticles with the typical sizes of 35 ± 5 nm. The as-synthesized nanoparticles were effectively used as an electrode material for the fabrication of efficient, highly sensitive and reproducible non-enzymatic glucose sensor. The fabricated glucose sensor shows a high and reproducible sensitivity of 38.133 μA/cm² mM with a response time less than 5 s. A linear dynamic range from 1∼10 mM and correlation coefficient of R = 0.9988 were observed for the fabricated sensor. The presented work demonstrated that the synthesized ZnO nanomaterials could act as effective electron mediators for the fabrication of efficient non-enzymatic glucose sensors.