Download PDF
Thromb Haemost 2007; 97(01): 151-152
DOI: 10.1160/TH06-10-0569
Case Report
Schattauer GmbH

The importance of tissue factor source in the management of Factor VII deficiency

Paula H. B. Bolton-Maggs
1   Manchester Haemophilia, Comprehensive Care Centre, Department of Clinical Haematology, Manchester Royal Infirmary, Manchester, UK
,
Charles R. M. Hay
1   Manchester Haemophilia, Comprehensive Care Centre, Department of Clinical Haematology, Manchester Royal Infirmary, Manchester, UK
,
Doreen Shanks
1   Manchester Haemophilia, Comprehensive Care Centre, Department of Clinical Haematology, Manchester Royal Infirmary, Manchester, UK
,
Michael J. Mitchell
2   Centre for Haemostasis and Thrombosis, Haemophilia Reference Centre, St. Thomas’ Hospital, London, UK
,
John H. McVey
3   Haemostasis and Thrombosis, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital Campus, London, UK
› Author Affiliations
Further Information

Publication History

Received 05 October 2006

Accepted after resubmission 22 November 2006

Publication Date:
28 November 2017 (online)

    Permissions and Reprints

 

 

  • References

  • 1 McVey JH, Boswell E, Mumford AD. et al Factor VII deficiency and the FVII mutation database. Hum Mutat 2001; 17: 3-17.
    CrossrefPubMedGoogle Scholar
  • 2 Perry DJ. Factor VII deficiency. B J Haematol 2002; 118: 689-700.
    CrossrefPubMedGoogle Scholar
  • 3 Bernardi F, Marchetti G, Pinotti M. et al Factor VII gene polymorphisms contribute about one third of the factor VII level variation in plasma. Arterioscler Thromb Vasc Biol 1996; 16: 72-6.
    CrossrefPubMedGoogle Scholar
  • 4 Pinotti M, Toso R, Girelli D. et al Modulation of factor VII levels by intron 7 polymorphisms: population and in vitro studies. Blood 2000; 95: 3423-8.
    CrossrefPubMedGoogle Scholar
  • 5 Alexander B, Goldstein R, Landwehr G. et al Congenital SPCA deficiency: a hitherto unrecognized coagulation defect with hemorrhage rectified by serum and serum fractions. J Clin Invest 1951; 30: 596-608.
    CrossrefPubMedGoogle Scholar
  • 6 Toso R, Tidd T, Arruda V. et al The absence of N-linked glycosylation in factor VII does not impair FVII activation or activity. Abstracts of the XVIIIth ISTH. Thromb Haemost 2001; Suppl P1398 (Abstract).
    PubMedGoogle Scholar
  • 7 Kemball-Cook G, Gomez K, Roscioli T. et al FVII deficiency due to homozygous FVII T324M mutation. J Thromb Haemost 2005; 3 (Suppl. 01) P0761.
    PubMedGoogle Scholar
  • 8 Takamiya O, Abe S, Yoshioka A. et al Factor VIIShinjo: a dysfunctional factor VII variant homozygous for the substitution Gln for Arg at position 79. Haemostasis 1995; 25: 89-97.
    PubMedGoogle Scholar
  • 9 O’Brien DP, Gale KM, Anderson JS. et al Purification and characterization of factor VII 304-Gln: a variant molecule with reduced activity isolated from a clinically unaffected male. Blood 1991; 78: 132-40.
    CrossrefPubMedGoogle Scholar
  • 10 Pollak ES, Russell TT, Ptashkin B. et al Asymptomatic factor VII deficiency in African Americans. Am J Clin Pathol 2006; 126: 128-32.
    CrossrefPubMedGoogle Scholar