1932
0
  1. Home
  2. A-Z Publications
  3. Annual Review of Immunology
  4. Volume 22, 2004
  5. Article

Annual Review of Immunology

Volume 22, 2004

Genetics, FACS, Immunology, and Redox: A Tale of Two Lives Intertwined

Preview Magnify

There is no abstract available.

Keyword(s): allotype, Autobiography, B cells, flow cytometry, glutathione, HIV
Loading

Article metrics loading...

/content/journals/10.1146/annurev.immunol.22.012703.104727
2004-04-23
2024-04-19
Loading full text...

Full text loading...

/deliver/fulltext/iy/22/1/annurev.immunol.22.012703.104727.html?itemId=/content/journals/10.1146/annurev.immunol.22.012703.104727&mimeType=html&fmt=ahah

Literature Cited

  1. Ames BN, Garry B, Herzenberg LA. 1.  1960. The genetic control of the enzymes of histidine biosynthesis in Salmonella typhimurium. J. Gen. Microbiol. 22:369–77 [Google Scholar]
  2. Herzenberg LA, Gonzales B. 2.  1962. Appearance of H-2 agglutinins in outcrossed female mice. Proc. Natl. Acad. Sci. USA 48:570–73 [Google Scholar]
  3. Herzenberg LA, Herzenberg LA. 3.  1961. Association of H-2 antigens with the cell membrane fraction of mouse liver. Proc. Natl. Acad. Sci. USA 47:762–67 [Google Scholar]
  4. Burnet FM. 4.  1959. The Clonal Selection Theory of Acquired Immunity. Cambridge, UK: Cambridge Univ. Press [Google Scholar]
  5. Wunderlich J, Herzenberg LA. 5.  1963. Genetics of a gamma globulin isoantigen (allotype) in the mouse. Proc. Natl. Acad. Sci. USA. 49:592–98 [Google Scholar]
  6. Herzenberg LA, Minna JD, Herzenberg LA. 6.  1967. A chromosome region for immunoglobulin heavy chains in the mouse: allelic electrophoretic mobility differences and allotype suppression. Cold Spring Harb. Symp. Quant. Biol. 32:181–86 [Google Scholar]
  7. Herzenberg LA. 7.  1964. A chromosome region for gamma2a and beta2A globulin H chain isoantigens in the mouse. Cold Spring Harb. Symp. Quant. Biol. 29:455–462 [Google Scholar]
  8. Herzenberg LA, Okumura K, Metzler CM. 8.  1975. Regulation of immunoglobulin and antibody production by allotype suppressor T cells in mice. Transplant. Rev. 27:57–83 [Google Scholar]
  9. Herzenberg LA, Tokuhisa T, Hayakawa K. 9.  1983. Epitope-specific regulation. Annu. Rev. Immunol. 1:609–32 [Google Scholar]
  10. Herzenberg LA, Black SJ. 10.  1980. Regulatory circuits and antibody responses. Eur. J. Immunol. 10:1–11 [Google Scholar]
  11. Van Dilla MA, Fulwyler MJ, Boone IU. 11.  1967. Volume distribution and separation of normal human leucocytes. Proc. Soc. Exp. Biol. Med. 125:367–70 [Google Scholar]
  12. Hulett HR, Bonner WA, Barrett J, Herzenberg LA. 12.  1969. Cell sorting: automated separation of mammalian cells as a function of intracellular fluorescence. Science 166:747–49 [Google Scholar]
  13. Bonner WA, Hulett HR, Sweet RG, Herzenberg LA. 13.  1972. Fluorescence activated cell sorting. Rev. Sci. Instrum. 43:404–9 [Google Scholar]
  14. Herzenberg LA, Sweet RG. 14.  1976. Fluorescence-activated cell sorting. Sci. Am. 234:108–17 [Google Scholar]
  15. Herzenberg LA. 15.  1973. Curing cancer by federal fiat. Hosp. Pract. 8:16 [Google Scholar]
  16. Oi VT, Jones PP, Goding JW, Herzenberg LA. 16.  1978. Properties of monoclonal antibodies to mouse Ig allotypes, H-2, and Ia antigens. Curr. Top. Microbiol. Immunol. 81:115–20 [Google Scholar]
  17. Milstein C, Herzenberg LA. 17. 1977 T and B Cell Hybrids. Presented at Regul. Gen. Immune Syst.: ICN-UCLA Symp. Mol. Cell. Biol.Los Angeles [Google Scholar]
  18. Ledbetter JA, Herzenberg LA. 18.  1979. Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens. Immunol. Rev. 47:63–90 [Google Scholar]
  19. Morrison SL, Johnson MJ, Herzenberg LA, Oi VT. 19.  1984. Chimeric human antibody molecules: mouse antigen-binding domains with human constant region domains. Proc. Natl. Acad. Sci. USA 81:6851–55 [Google Scholar]
  20. Parks DR, Bryan VM, Oi VT, Herzenberg LA. 20.  1979. Antigen-specific identification and cloning of hybridomas with a fluorescence-activated cell sorter. Proc. Natl. Acad. Sci. USA 76:1962–66 [Google Scholar]
  21. Parks DR, Hardy Richard A, Herzenberg LA. 21.  1983. Dual immunofluorescence—new frontiers in cell analysis and sorting. Immunol. Today 4:145–50 [Google Scholar]
  22. Parks DR, Hardy RR, Herzenberg LA. 22.  1984. Three-color immunofluorescence analysis of mouse B-lymphocyte subpopulations. Cytometry 5:159–68 [Google Scholar]
  23. De Rosa SC, Herzenberg LA, Herzenberg LA, Roederer M. 23.  2001. 11 color, 13 parameter flow cytometry: identification of naive T cells by phenotype, function and T cell receptor. Nat. Med. 7:245–48 [Google Scholar]
  24. Baumgarth N, Roederer M. 24.  2000. A practical approach to multicolor flow cytometry for immunophenotyping. J. Immunol. Methods 243:77–97 [Google Scholar]
  25. Roederer M, Herzenberg LA. 25.  1999. Flow cytometry. In Encyclopedia of Molecular Biology ed. TE Creighton pp. 1–4 New York: Wiley [Google Scholar]
  26. Moore W, Kautz R. 26.  1986. Data analysis for flow cytometry. In The Handbook of Experimental Immunology ed. LA Herzenberg, DM Weir, CC Blackwell, LA Herzenberg Edinburgh: Blackwell Scientific pp. 30–36 [Google Scholar]
  27. Herzenberg LA, Ledbetter JA. 27.  1979. Monoclonal antibodies and the fluorescence-activated cell sorter: complementary tools in lymphoid cell biology. In Molecular Basis of Immune Cell Function pp. 315–30 Amsterdam: Elsevier/North-Holland Biomedical [Google Scholar]
  28. Jones PP, Cebra JJ, Herzenberg LA. 28.  1973. Immunoglobulin (Ig) allotype markers on rabbit lymphocytes: separation of cells bearing different allotypes and demonstration of the binding of Ig to lymphoid cell membranes. J. Immunol. 111:1334–48 [Google Scholar]
  29. Jones PP, Tacier-Eugster H, Herzenberg LA. 29.  1974. Lymphocyte commitment to Ig allotype and class. Ann. Immunol. (Paris) 125C:271–76 [Google Scholar]
  30. Jones PP, Craig SW, Cebra JJ, Herzenberg LA. 30.  1974. Restriction of gene expression in B lymphocytes and their progeny. II. Commitment to immunoglobulin heavy chain isotype J. Exp. Med. 140:452–69 [Google Scholar]
  31. Okumura K, Julius MH, Tsu T, Herzenberg LA. 31.  1976. Demonstration that IgG memory is carried by IgG-bearing cells. Eur. J. Immunol. 6:467–72 [Google Scholar]
  32. Julius MH, Masuda T, Herzenberg LA. 32.  1972. Demonstration that antigen-binding cells are precursors of antibody-producing cells after purification with a fluorescence-activated cell sorter. Proc. Natl. Acad. Sci. USA 69:1934–38 [Google Scholar]
  33. Julius MH, Janeway CA Jr., Herzenberg LA. 33.  1976. Isolation of antigen-binding cells from unprimed mice. II. Evidence for monospecificity of antigen-binding cells Eur. J. Immunol. 6:288–92 [Google Scholar]
  34. Hardy RR, Hayakawa K, Haaijman J, Herzenberg LA. 34.  1982. B-cell subpopulations identified by two-colour fluorescence analysis. Nature 297:589–91 [Google Scholar]
  35. Hardy RR, Hayakawa K, Parks DR, Herzenberg LA. 35.  1983. Demonstration of B-cell maturation in X-linked immunodeficient mice by simultaneous three-colour immunofluorescence. Nature 306:270–72 [Google Scholar]
  36. Hardy RR, Hayakawa K, Parks DR, Herzenberg LA. 36.  1984. Murine B cell differentiation lineages. J. Exp. Med. 159:1169–88 [Google Scholar]
  37. Hayakawa K, Hardy RR, Parks DR, Herzenberg LA. 37.  1983. The “Ly-1 B” cell subpopulation in normal immunodefective, and autoimmune mice. J. Exp. Med. 157:202–18 [Google Scholar]
  38. Li YS, Hayakawa K, Hardy RR. 38.  1993. The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver. J. Exp. Med. 178:951–60 [Google Scholar]
  39. Herzenberg LA, Kantor AB. 39.  1993. B-cell lineages exist in the mouse. Immunol. Today 14:79–83 discussion 8–90 [Google Scholar]
  40. Wortis HH, Berland R. 40.  2001. Cutting edge commentary: origins of B-1 cells. J. Immunol. 166:2163–66 [Google Scholar]
  41. Stall AM, Adams S, Herzenberg LA, Kantor AB. 41.  1992. Characteristics and development of the murine B-1b (Ly-1 B sister) cell population. Ann. NY Acad. Sci. 651:33–43 [Google Scholar]
  42. Kantor AB, Herzenberg LA. 42.  1993. Origin of murine B cell lineages. Annu. Rev. Immunol. 11:501–38 [Google Scholar]
  43. de Waard R, Dammers PM, Tung JW, Kantor AB, Wilshire JA. 43.  et al. 1998. Presence of germline and full-length IgA RNA transcripts among peritoneal B-1 cells. Dev. Immunol. 6:81–87 [Google Scholar]
  44. Herzenberg LA. 44.  2000. B-1 cells: the lineage question revisisted. Immunol. Reviews 175:9–21 [Google Scholar]
  45. Baumgarth N, Herman OC, Jager GC, Brown LE, Herzenberg LA, Chen J. 45.  2000. B-1 and B-2 cell-derived immunoglobulin M antibodies are nonredundant components of the protective response to influenza virus infection. J. Exp. Med. 192:271–80 [Google Scholar]
  46. Herzenberg LA, Okumura K, Cantor H, Sato VL, Shen FW, Boyse EA. 46.  1976. T-cell regulation of antibody responses: demonstration of allotype-specific helper T cells and their specific removal by suppressor T cells. J. Exp. Med. 144:330–44 [Google Scholar]
  47. Ledbetter J, Goding JW, Tokuhisa T, Herzenberg LA. 47.  1980. Murine T cell differentiation and antigens detected by monoclonal antibodies. In Monoclonal Antibodies pp. 235–49 New York: Plenum [Google Scholar]
  48. Goding JW, Herzenberg LA. 48.  1980. Biosynthesis of lymphocyte surface IgD in the mouse. J. Immunol. 124:2540–47 [Google Scholar]
  49. Howard FD, Ledbetter JA, Wong J, Bieber CP, Stinson EB, Herzenberg LA. 49.  1981. A human T lymphocyte differentiation marker defined by monoclonal antibodies that block E-rosette formation. J. Immunol. 126:2117–22 [Google Scholar]
  50. Lanier LL, Warner NL, Ledbetter JA, Herzenberg LA. 50.  1981. Quantitative immunofluorescent analysis of surface phenotypes of murine B cell lymphomas and plasmacytomas with monoclonal antibodies. J. Immunol. 127:1691–97 [Google Scholar]
  51. Waldor MK, Sriram S, Hardy R, Herzenberg LA, Lanier L. 51.  et al. 1985. Reversal of experimental allergic encephalomyelitis with monoclonal antibody to a T-cell subset marker. Science 227:415–17 [Google Scholar]
  52. Kipps TJ, Herzenberg LA. 52.  1986. Hybridoma immunoglobulin isotype switch variant selection using the fluorescence activated cell sorter. In The Handbook of Experimental Immunology ed. LA Herzenberg, DM Weir, CC Blackwell, LA Herzenberg Edinburgh: Blackwell Scientific pp. 109.1–109.8 [Google Scholar]
  53. Dialynas DP, Quan ZS, Wall KA, Pierres A, Quintans J. 53.  et al. 1983. Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule. J. Immunol. 131:2445–51 [Google Scholar]
  54. Ledbetter JA, Evans RL, Lipinski M, Cunningham-Rundles C, Good RA, Herzenberg LA. 54.  1981. Evolutionary conservation of surface molecules that distinguish T lymphocyte helper/inducer and cytotoxic/suppressor subpopulations in mouse and man. J. Exp. Med. 153:310–23 [Google Scholar]
  55. Roederer M, Dubs JG, Anderson MT, Raju PA, Herzenberg LA. 55.  1995. CD8 naive T cell counts decrease progressively in HIV-infected adults. J. Clin. Invest. 95:2061–66 [Google Scholar]
  56. Watanabe N, De Rosa SC, Cmelak A, Hoppe R, Herzenberg LA, Roederer M. 56.  1997. Long-term depletion of naive T cells in patients treated for Hodgkin's disease. Blood 90:3662–72 [Google Scholar]
  57. Sahaf B, Heydari K, Herzenberg LA. 57.  2003. Lymphocyte surface thiol levels. Proc. Natl. Acad. Sci. USA 100:4001–5 [Google Scholar]
  58. Perez OD, Nolan GP, Magda D, Miller RA, Herzenberg LA, Herzenberg LA. 58.  2002. Motexafin gadolinium (Gd-Tex) selectively induces apoptosis in HIV-1 infected CD4+ T helper cells. Proc. Natl. Acad. Sci. USA 99:2270–74 [Google Scholar]
  59. Lu L-S, Tung J, Baumgarth N, Herman O, Gleimer M. 59.  et al. 2002. Identification of a germ-line pro-B cell subset that distinguishes the fetal/neonatal from the adult B cell development pathway. Proc. Natl. Acad. Sci. USA 99:3007–12 [Google Scholar]
  60. De Rosa SC, Brenchley JM, Roederer M. 60.  2003. Beyond six colors: a new era in flow cytometry. Nat. Med. 9:112–17 [Google Scholar]
  61. Herzenberg LA, De Rosa SC, Herzenberg LA. 61.  2000. Monoclonal antibodies and the FACS: complementary tools for immunobiology and medicine. Immunol. Today 21:383–90 [Google Scholar]
  62. Kipps TJ, Herzenberg LA. 62.  1986. Homologous chromosome recombination generating immunoglobulin allotype and isotype switch variants. EMBO J. 5:263–68 [Google Scholar]
  63. Huang HJ, Jones NH, Strominger JL, Herzenberg LA. 63.  1987. Molecular cloning of Ly-1, a membrane glycoprotein of mouse T lymphocytes and a subset of B cells: molecular homology to its human counterpart Leu-1/T1 (CD5). Proc. Natl. Acad. Sci. USA 84:204–8 [Google Scholar]
  64. Kavathas P, Sukhatme VP, Herzenberg LA, Parnes JR. 64.  1984. Isolation of the gene encoding the human T-lymphocyte differentiation antigen Leu-2 (T8) by gene transfer and cDNA subtraction. Proc. Natl. Acad. Sci. USA 81:7688–92 [Google Scholar]
  65. Nakauchi H, Nolan GP, Hsu C, Huang HS, Kavathas P, Herzenberg LA. 65.  1985. Molecular cloning of Lyt-2, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to its human counterpart, Leu-2/T8, and to immunoglobulin variable regions. Proc. Natl. Acad. Sci. USA 82:5126–30 [Google Scholar]
  66. Kavathas P, Herzenberg LA. 66.  1983. Amplification of a gene coding for human T-cell differentiation antigen. Nature 306:385–87 [Google Scholar]
  67. Herzenberg LA, Bianchi DW, Schroder J, Cann HM, Iverson GM. 67.  1979. Fetal cells in the blood of pregnant women: detection and enrichment by fluorescence-activated cell sorting. Proc. Natl. Acad. Sci. USA 76:1453–55 [Google Scholar]
  68. Johnson KL, Nelson JL, Furst DE, McSweeney PA, Roberts DJ. 68.  et al. 2001. Fetal cell microchimerism in tissue from multiple sites in women with systemic sclerosis. Arthritis Rheum. 44:1848–54 [Google Scholar]
  69. Srivatsa B, Srivatsa S, Johnson KL, Bianchi DW. 69.  2003. Maternal cell microchimerism in newborn tissues. J. Pediatr. 142:31–35 [Google Scholar]
  70. Droge W, Eck HP, Mihm S. 70.  1992. HIV-induced cysteine deficiency and T-cell dysfunction—a rationale for treatment with N-acetylcysteine. Immunol. Today 13:211–14 [Google Scholar]
  71. Kinscherf R, Fischbach T, Mihm S, Roth S, Hohenhaus-Sievert E. 71.  et al. 1994. Effect of glutathione depletion and oral N-acetyl-cysteine treatment on CD4+ and CD8+ cells. FASEB J. 8:448–51 [Google Scholar]
  72. Roederer M, Raju PA, Staal FJ, Herzenberg LA, Herzenberg LA. 72.  1991. N-acetylcysteine inhibits latent HIV expression in chronically infected cells. AIDS Res. Hum. Retroviruses 7:563–67 [Google Scholar]
  73. Montano MA, Kripke K, Norina CD, Achacoso P, Herzenberg LA. 73.  et al. 1996. NF-kappa B homodimer binding within the HIV-1 initiator region and interactions with TFII-I. Proc. Natl. Acad. Sci. USA 93:12376–81 [Google Scholar]
  74. Staal FJ, Roederer M, Raju PA, Anderson MT, Ela SW. 74.  et al. 1993. Antioxidants inhibit stimulation of HIV transcription. AIDS Res. Hum. Retroviruses 9:299–306 [Google Scholar]
  75. Breitkreutz R, Pittack N, Nebe CT, Schuster D, Brust J. 75.  et al. 2000. Improvement of immune functions in HIV infection by sulfur supplementation: two randomized trials. J. Mol. Med. 78:55–62 [Google Scholar]
  76. De Rosa SC, Zaretsky MD, Dubs JG, Roederer M, Anderson M. 76.  et al. 2000. N-acetylcysteine (NAC) replenishes glutathione in HIV infection. Eur. J. Clin. Invest. 30:841–56 [Google Scholar]
  77. Herzenberg LA, De Rosa SC, Dubs JG, Roederer M, Anderson MT. 77.  et al. 1997. Glutathione deficiency is associated with impaired survival in HIV disease. Proc. Natl. Acad. Sci. USA 94:1967–72 [Google Scholar]
  78. Ghezzi P, Romines B, Fratelli M, Eberini I, Gianazza E. 78.  et al. 2002. Protein glutathionylation: coupling and uncoupling of glutathione to protein thiol groups in lymphocytes under oxidative stress and HIV infection. Mol. Immunol. 38:773–80 [Google Scholar]
  79. Nakamura H, De Rosa S, Roederer M, Anderson MT, Dubs JG. 79.  et al. 1996. Elevation of plasma thioredoxin levels in HIV-infected individuals. Int. Immunol. 8:603–11 [Google Scholar]
  80. Nakamura H, Herzenberg LA, Bai J, Araya S, Kondo N. 80.  et al. 2001. Circulating thioredoxin suppresses lipopolysaccharide-induced neutrophil chemotaxis. Proc. Natl. Acad. Sci. USA 98:15143–48 [Google Scholar]
  81. Nakamura H, De Rosa SC, Roederer M, Yodoi J, Holmgren A. 81.  et al. 2001. Chronic elevation of plasma thioredoxin: inhibition of chemotaxis and curtailment of life expectancy in AIDS. Proc. Natl. Acad. Sci. USA 98:(5)2688–93 [Google Scholar]
/content/journals/10.1146/annurev.immunol.22.012703.104727
Loading
  • Article Type: Review Article

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error