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Patchy atrophy and lacquer cracks predispose to the development of choroidal neovascularisation in pathological myopia
  1. K Ohno-Matsui,
  2. T Yoshida,
  3. S Futagami,
  4. K Yasuzumi,
  5. N Shimada,
  6. A Kojima,
  7. T Tokoro,
  8. M Mochizuki
  1. Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan
  1. Correspondence to: Kyoko Ohno-Matsui, MD, Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113, Japan; k.ohno.oph{at}med.tmd.ac.jp

Abstract

Aims: To determine the incidence and predisposing findings for choroidal neovascularisation (CNV) in a large series of highly myopic patients.

Methods: The medical records of 218 consecutive patients (325 eyes) with myopic fundus changes in the macula were reviewed. The incidence of CNV during a follow up of at least 3 years of highly myopic patients and identification of predisposing findings for the development of myopic CNV were examined.

Results: Among 325 highly myopic eyes examined, 33 eyes (10.2%) developed myopic CNV. The incidence was higher (34.8%) among the fellow eyes of patients with pre-existing CNV than among eyes of patients without pre-existing CNV (6.1%). CNV developed in 3.7% with diffuse chorioretinal atrophy, in 20.0% with patchy atrophy, and in 29.4% with lacquer cracks.

Conclusion: Approximately one in 10 highly myopic eyes developed myopic CNV in average 130.2 months. Patchy atrophy and lacquer cracks were shown to be important predisposing findings for CNV development.

  • choroidal neovascularisation
  • myopia

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