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Hypoxia as pathogenic factor affecting the eye tissues: The selective apoptotic damage of the conjunctiva and anterior epithelium of the cornea

  • Biochemistry, Biophysics and Molecular Biology
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Abstract

The effect of acute hypoxia on the occurrence of apoptosis in eye cells in rats placed in a pressure chamber was studied. Selective primary lesion of cells of the conjunctiva and the anterior corneal epithelium was found. A possible role of the simulated hypoxic conditions in the dry eye syndrome pathogenesis, which is accompanied by primary lesion of cells in the anterior eye surface tissues is discussed.

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Correspondence to Yu. V. Markitantova.

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Original Russian Text © S.I. Akberova, Yu.V. Markitantova, A.A. Ryabtseva, O.G. Stroeva, 2016, published in Doklady Akademii Nauk, 2016, Vol. 467, No. 6, pp. 718–720.

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Akberova, S.I., Markitantova, Y.V., Ryabtseva, A.A. et al. Hypoxia as pathogenic factor affecting the eye tissues: The selective apoptotic damage of the conjunctiva and anterior epithelium of the cornea. Dokl Biochem Biophys 467, 150–152 (2016). https://doi.org/10.1134/S1607672916020198

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  • DOI: https://doi.org/10.1134/S1607672916020198

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