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Three-component synthesis of 3-(diarylmethyl)indoles using Fe(ClO4)3/SiO2 as catalyst

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Abstract

Three-component reaction of indole, aromatic aldehyde, and N,N-dimethyl aniline in the presence of silica-supported Fe(ClO4)3 as catalyst afforded the corresponding 3-[aryl(4-dimethylaminophenyl)methyl]-indoles in excellent yields under mild conditions. The proposed protocol offers some remarkable advantages such as the use of a solid catalyst and simple workup procedure.

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Authors and Affiliations

  1. Department of Chemistry, Karaj Branch, Islamic Azad University, Karaj, Iran, 31485313

    E. Najafi & F. K. Behbahani

Authors
  1. E. Najafi
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  2. F. K. Behbahani
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Correspondence to F. K. Behbahani.

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The text was submitted by the authors in English.

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Najafi, E., Behbahani, F.K. Three-component synthesis of 3-(diarylmethyl)indoles using Fe(ClO4)3/SiO2 as catalyst. Russ J Org Chem 53, 454–458 (2017). https://doi.org/10.1134/S107042801703023X

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  • DOI: https://doi.org/10.1134/S107042801703023X

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