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Amidophenacylating reagents in synthesis of new derivatives of 1,3-oxazole- and 1,3-thiazole-4-sulfonyl chlorides and corresponding sulfonamides

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Abstract

Derivatives of 4-benzylsulfanyl-1,3-oxazole and 4-benzylsulfanyl-1,3-thiazole were synthesized using available amidophenacylating reagents. By the oxidative chlorination compounds obtained were converted to 1,3-oxazole-4-sulfonyl and 1,3-thiazol-4-sulfonyl chlorides. The latter were used to prepare the corresponding sulfonamides.

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Authors and Affiliations

  1. Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine, ul. Murmanskaya 1, Kiev, 02660, Ukraine

    A. N. Kornienko, S. G. Pil’o, V. M. Prokopenko & V. S. Brovarets

Authors
  1. A. N. Kornienko
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  2. S. G. Pil’o
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  3. V. M. Prokopenko
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  4. V. S. Brovarets
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Correspondence to V. S. Brovarets.

Additional information

Original Russian Text © A.N. Kornienko, S.G. Pil’o, V.M. Prokopenko, V.S. Brovarets, 2014, published in Zhurnal Obshchei Khimii, 2014, Vol. 84, No. 4, pp. 607–613.

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Kornienko, A.N., Pil’o, S.G., Prokopenko, V.M. et al. Amidophenacylating reagents in synthesis of new derivatives of 1,3-oxazole- and 1,3-thiazole-4-sulfonyl chlorides and corresponding sulfonamides. Russ J Gen Chem 84, 686–692 (2014). https://doi.org/10.1134/S1070363214040148

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  • DOI: https://doi.org/10.1134/S1070363214040148

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