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Optimization of a hydrogen bromide fission procedure for nonyl- and dinonylphenol polyethoxylates and their o-phosphate esters

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Abstract

Nonyl- and dinonylphenol polyethoxylates (NPEOs, DNPEOs) and their o-phosphate esters are widely used as surfactants in various industrial, agricultural and domestic applications. An HBr-fission procedure was developed for cleaving NPEOs, DNPEOs and their o-phosphate esters to nonylphenol (NP) and dinonylphenol (DNP), and their bromine adducts, thereby facilitating the analysis of NP- and DNP contents in complex NPEO- and DNPEO-containing samples. The procedure includes fission, liquid-liquid extraction and GC-MS analyses of the fission end-products. Using 2 × 2 factorial experimental designs, 2 h cleavage at 120°C was found to provide optimal yields of the target compounds, with minimal unwanted by-products. The calculated accuracy for the cleavage of NP10EO to NP was 95% and the limit of NP/DNP detection of the presented method was 5 mg/L.

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Authors and Affiliations

  1. GE Healthcare, Quality Control Support, Björkgatan 30, Uppsala, S-75184, Sweden

    Å. Stenholm & S. Holmström

  2. GE Healthcare, Reseach & Development, Björkgatan 30, Uppsala, S-75184, Sweden

    I. Drevin

Authors
  1. Å. Stenholm
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  2. S. Holmström
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  3. I. Drevin
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Stenholm, Å., Holmström, S. & Drevin, I. Optimization of a hydrogen bromide fission procedure for nonyl- and dinonylphenol polyethoxylates and their o-phosphate esters. J Anal Chem 66, 1173–1179 (2011). https://doi.org/10.1134/S1061934811120100

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  • DOI: https://doi.org/10.1134/S1061934811120100

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