Abstract
Method of capillary electrophoresis with a diode-array detector was used to study the conditions of the separation of three alkyl methylphosphonates and methylphosphonic acid, hydrolysis products of nerve agents. The optimal conditions providing their separation and determination are reported (background electrolyte based on 100 mM boric acid with the addition of 10 mM of phenylphosphonic acid (pH 6.0); voltage +30 kV, detection wavelength 210 nm, electrokinetic introduction of the sample (10 kV, 10 sec), separation time below 10 min). Calibration curve for all the compounds was linear in the concentration range 0.05–1.0 mg/mL, the correlation coefficient was 0.999 in all cases. The procedure was tested for river and ground waters containing a mixture of isopropyl, isobutyl, pinacolyl methylphosphonates and methylphosphonic acid. Relative standard deviations of the migration times under the conditions of the repeatability of the results lie in the range 1.9–2.7% (n = 5), the relative standard deviation of the reduced peak areas vary from 1.2 to 7.0%.
Similar content being viewed by others
References
Savel’eva, E.I., Radilov, A.S., Kuznetsova, T.A., and Volynets, N.F., Zh. Prikl. Khim., 2001, vol. 74, no. 10, p. 1671 [Russ. J. Appl. Chem. (Engl. Transl.), vol. 74, no. 10, p. 1722].
Hooijschuur, E.W.J., Kientz, Ch.E., and Brinkman, U.A.Th., J. Chromatogr. A, 2002, vol. 982, p. 177.
Stan’kov, I.N., Mylova, S.N., Sergeeva, A.A., et al., Zh. Anal. Khim., 2007, vol. 62, no. 2, p. 158 [J. Anal. Chem. (Engl. Transl.), vol. 62, no. 2, p. 141].
Stan’kov, I.N., Derevyagina, I.D., Kondrat’ev, V.B., et al., Zh. Anal. Khim., 2008, vol. 63, no. 7, p. 731 [J. Anal. Chem. (Engl. Transl.), vol. 63, no. 7, p. 668].
Vasilevskii, S.V., Kireev, A.F., Rybal’chenko, I.V., and Suvorkin, V.N., Zh. Anal. Khim., 2002, vol. 57, no. 6, p. 597 [J. Anal. Chem. (Engl. Transl.), vol. 57, no. 6, p. 491].
Kireev, A.F., Rybal’chenko, I.V., Savchuk, V.I., and Suvorkin, V.N., Zh. Anal. Khim., 2002, vol. 57, no. 6, p. 637 [J. Anal. Chem. (Engl. Transl.), vol. 57, no. 6, p. 529].
Mercier, J.-P., Morin, Ph., Dreux, M., and Tambute, A., J. Chromatogr. A, 1997, vol. 779, p. 245.
Nassar, A.-E.F., Lucas, S.V., Jones, W.R., and Hoffland, L.D., Anal. Chem., 1998, vol. 70, p. 1085.
Kostiainen, R., Bruins, A.P., and Hakkinen, V.M.A., J. Chromatogr., 1993, vol. 634, p. 113.
Lagarrigue, M., Bossee, A., Begos, A., Delaunay, N., Varenne, A., Gareil, P., and Bellier, B., J. Chromatogr. A, 2008, vol. 1178, p. 239.
Nassar, A.-E.F., Lucas, S.V., and Hoffland, L.D., Anal. Chem., 1999, vol. 71, p. 1285.
Kubachka, K.M., Richardson, D.D., Heitkemper, D.T., and Caruso, J.A., J. Chromatogr. A, 2008, vol. 1202, p. 124.
Melanson, J.E., Wong, B.L.-Y., Boulet C.A., and Lucy Ch.A., J. Chromatogr. A, 2001, vol. 920, p. 359.
Author information
Authors and Affiliations
Additional information
Original Russian Text © S.S. Aleksenko, S.V. Tret’yakova, V.G. Mandych, 2011, published in Zhurnal Analiticheskoi Khimii, 2011, Vol. 66, No. 4, pp. 431–434.
Rights and permissions
About this article
Cite this article
Aleksenko, S.S., Tret’yakova, S.V. & Mandych, V.G. Determination of alkyl methylphosphonates and methylphosphonic acid by capillary electrophoresis with a diode-array spectrophotometric detector. J Anal Chem 66, 421–424 (2011). https://doi.org/10.1134/S1061934811040022
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S1061934811040022