Abstract
Numerous species of the genus Aloe have attracted the attention of researchers because of their different biological benefits and their capacity to act as antioxidants. This paper presents a comparative study of the kinetics of the inhibitory effect of ethanol extracts of five species of Aloe, which was made using a model system of the oxidation of phosphatidylcholine liposomes. It was found that plant extracts of A. marlothii and A. congolensis have higher antioxidant activities (by a factor of 13 and 10, respectively) than the best known Aloe species: A. arborescens and A. vera. The total phenolic content values of A. marlothii and A. congolensis are higher than those of A. arborescens and A. vera but to a lesser degree (by a factor of 5–6) than antioxidant activity. This may indicate the presence of very active phenolic antioxidants in A. Marlothii and A. congolensis. An analysis of the influence of extracts introduced into liposomes on liposome size showed that the most active extracts of A. marlothii, A. congolensis, and A. pillansii reduce the average liposome size compared to pure liposomes, and extracts with weaker antioxidant activity increase it, which is probably due to changes in the lipid structure of liposomes by the components of extracts. Based on the results we obtained, A. marlothii, A. congolensis, and A. pillansii are suitable for studying other types of their biological activity that might contribute to new drug development.
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Sazhina, N.N., Lapshin, P.V. & Zagoskina, N.V. The Kinetics of Initiated Oxidation of Phosphatidylcholine Liposomes with Introduced Aloe Extracts and Determination of their Antioxidant Activity. BIOPHYSICS 66, 420–427 (2021). https://doi.org/10.1134/S0006350921030155
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DOI: https://doi.org/10.1134/S0006350921030155