Abstract
On the basis of our earlier experiments on the study of changes in the content of titin and the level of its phosphorylation in skeletal muscles that atrophied during space flight, hibernation, and because of the development of alcohol-induced lesions, it was hypothesized that an increase in the degree of titin phosphorylation results in increased proteolytic degradation of this protein, which contributes to the development of skeletal muscle atrophy.
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Original Russian Text © N.N. Salmov, Yu.V. Gritsyna, A.D. Ulanova, I.M. Vikhlyantsev, Z.A. Podlubnaya, 2015, published in Biofizika, 2015, Vol. 60, No. 4, pp. 829–832.
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Salmov, N.N., Gritsyna, Y.V., Ulanova, A.D. et al. On the role of titin phosphorylation in the development of muscular atrophy. BIOPHYSICS 60, 684–686 (2015). https://doi.org/10.1134/S0006350915040193
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DOI: https://doi.org/10.1134/S0006350915040193