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Do external or internal factors lead to tumor development? It is still unknown

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Abstract

Arguments supporting the “bad luck” hypothesis presented by C. Tomasetti and B. Vogelstein ((2015) Science, 347, 78–81) and A. V. Lichtenstein ((2017) Biochemistry (Moscow), 82, 75–80) are critically discussed. Those arguments are not sufficient for recognition of the “bad luck” hypothesis and the leading role of internal factors in spontaneous tumor development.

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Authors and Affiliations

  1. Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119991, Moscow, Russia

    V. N. Manskikh

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  1. V. N. Manskikh
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Correspondence to V. N. Manskikh.

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Published in Russian in Biokhimiya, 2017, Vol. 82, No. 1, pp. 175-180.

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Manskikh, V.N. Do external or internal factors lead to tumor development? It is still unknown. Biochemistry Moscow 82, 81–85 (2017). https://doi.org/10.1134/S0006297917010096

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