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Regulatory functions of microtubules

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Abstract

This mini-review summarizes literature and original data about the role of microtubules in interphase animal cells. Recent data have shown that functioning of microtubules is essential for such diverse phenomena as directional cell movements, distribution of organelles in the cytoplasm, and neuronal memory in the central nervous system. It is suggested that microtubules can act as an important regulatory system in eukaryotic cells. Possible mechanisms of these functions are discussed.

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References

  1. Vasiliev, J. M., Gelfand, I. M., and Domnina, L. V. (1969) Exp. Cell Res.,. 54, 83–93.

    Article  PubMed  CAS  Google Scholar 

  2. Vasiliev, J. M., Gelfand, I. M., Domnina, L. V., Ivanova, O. Y., Komm, S. G., and Olshevskaya, L. V. (1970) J. Embryol. Exp. Morphol., 24, 625–640.

    PubMed  CAS  Google Scholar 

  3. Ivanova, O. Y., Margolis, L. B., Vasiliev, J. M., and Gelfand, I. M. (1976) Exp. Cell. Res., 101, 207–219.

    Article  PubMed  CAS  Google Scholar 

  4. Vasiliev, J. M. (2007) Ontogenesis, 38, 120–125.

    Google Scholar 

  5. Miller, P. M., Folkman, A. W., Maia, A. R., Efimova, N., Efimov, A., and Kaverina, I. (2009) Nat. Cell Biol., 1, 1069–1080.

    Article  Google Scholar 

  6. Craddock, J. A., Tuszynski, J. A., and Hameroff, S. (2012) PloS Comput. Biol., 8, 1–16.

    Article  Google Scholar 

  7. Abercromby, M. (1980) Proc. R. Soc. Lond., B, 207, 129–147.

    Article  Google Scholar 

  8. Chentsov, Y. S. (2004) Introduction into Cellular Biology [in Russian], Akademkniga, Moscow.

    Google Scholar 

  9. Chentsov, Y. S. (2010) Cytology with Elements of Cellular Pathology [in Russian], Med. Inform. Agency, Moscow.

    Google Scholar 

  10. Kirschner, M., and Mitchison, T. (1986) Cell, 45, 329–342.

    Article  PubMed  CAS  Google Scholar 

  11. Cole, N. B., Ciaky, N., Marotta, A., Song, J., and Lippingcot-Schwartz, G. (1996) Mol. Biol. Cell, 7, 631–650.

    PubMed  CAS  Google Scholar 

  12. Burhardt, J. K. (1998) Biochim. Biophys. Acta, 1404, 113–126.

    Article  Google Scholar 

  13. Thiberg, J., and Moskalewski, S. (1999) Exp. Cell Res., 246, 263–270.

    Article  Google Scholar 

  14. Allan, V. J., Thompson, H. M., and McNiven, M. A. (2002) Nature Cell Biol., 4, E236–242.

    Article  PubMed  CAS  Google Scholar 

  15. Small, J. V., Geiger, I., Kaverina, I., and Bershadsky, A. (2002) Nature Rev. Mol. Cell Biol., 2, 957.

    Article  Google Scholar 

  16. Joe, P. A., Bannerje, A., and Luden, R. F. (2003) Nature Cell Mol., 5, 599–609.

    Article  Google Scholar 

  17. Rodriguez, O. C., Schaefer, A. W., Mandato, C. A., Forscher, P., Bement, W. M., and Waterman-Storer, C. M. (2003) Nature Cell Biol., 5, 599–609.

    Article  PubMed  CAS  Google Scholar 

  18. Small, J. V., and Kaverina, I. (2003) Curr. Opin. Cell Biol., 15, 40–47.

    Article  PubMed  CAS  Google Scholar 

  19. Daly, R. J. (2004) Biochem. J., 382, 13–25.

    Article  PubMed  CAS  Google Scholar 

  20. Prigozhina, N. L., and Waterman-Storer, C. M. (2004) Curr. Biol., 14, 88–98.

    Article  PubMed  CAS  Google Scholar 

  21. Rios, R. M., Sanchis, A., Tassin, A. V., Fedriani, C., and Bornens, M. (2004) Cell, 118, 271–272.

    Article  Google Scholar 

  22. Witmann, T., and Waterman-Storer, C. M. (2005) J. Cell Biol., 169, 929–939.

    Article  Google Scholar 

  23. Puthenveedu, M. A., Bachert, C., Puri, S., Lanni, F., and Linstedt, A. D. (2006) Nature Cell Biol., 8, 238–248.

    Article  PubMed  CAS  Google Scholar 

  24. Efimov, A., Kharitonov, A., Efimova, N., Lonkarek, J., Miller, P. M., Andreeva, N., Gleeson, P., Galjart, N., Maia, A. R., McLeod, I. X., Yates, J. R., III, Maiato, H., Khodiakov, A., Akhmanova, A., and Kaverina, I. (2007) Dev. Cell, 12, 917–930.

    Article  PubMed  CAS  Google Scholar 

  25. Bomens, M. (2008) Nature Res. Mol. Cell Biol., 9, 874–886.

    Article  Google Scholar 

  26. Feinstein, T. N., and Linstedt, A. D. (2008) Mol. Biol. Cell, 19, 2896–2707.

    Article  Google Scholar 

  27. Tang, D. (2008) J. Biol. Chem., 283, 6085–6094.

    Article  PubMed  CAS  Google Scholar 

  28. Yadav, S., Puri, S., and Linstedt, A. D. (2009) Mol. Biol. Cell, 20, 1728–1736.

    Article  PubMed  CAS  Google Scholar 

  29. Rodionov, V. I., Nadezhdina, E. S., Leonova, E. V., Vaisberg, E. A., Kuznetsov, S. A., and Gelfand, V. I. (1985) Exp. Cell Res., 159, 377–387.

    Article  PubMed  CAS  Google Scholar 

  30. Reilein, A. R., Serpinskaya, A. S., Karcher, R. L., Dujardin, D. L., Valee, R. B., and Gelfand, V. I. (2003) Biochem. Biophys. Res. Commun., 309, 652–658.

    Article  PubMed  CAS  Google Scholar 

  31. Minin, A. A., Kulik, A. V., Gyoeva, F. K., Li, Y., Goshima, G., and Gelfand, V. I. (2006) J. Cell Sci., 119, 659–669.

    Article  PubMed  CAS  Google Scholar 

  32. Cronly-Dillon, J., Garden, D., and Birks, C. (1974) J. Exp. Biol., 6, 443–451.

    Google Scholar 

  33. Tagchi, M., and Chida, K. (2008) Acta Histochem. Cytochem., 41, 149–155.

    Article  Google Scholar 

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Authors and Affiliations

  1. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119991, Moscow, Russia

    J. M. Vasiliev & V. I. Samoylov

Authors
  1. J. M. Vasiliev
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  2. V. I. Samoylov
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Correspondence to J. M. Vasiliev.

Additional information

Original Russian Text © J. M. Vasiliev, V. I. Samoylov, 2013, published in Biokhimiya, 2013, Vol. 78, No. 1, pp. 48–51.

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Vasiliev, J.M., Samoylov, V.I. Regulatory functions of microtubules. Biochemistry Moscow 78, 37–40 (2013). https://doi.org/10.1134/S0006297913010045

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  • DOI: https://doi.org/10.1134/S0006297913010045

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