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The First Autosomal STR Population Data of Kinh Ethinic Group in Vietnam by Using Massively Parallel Sequencing

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Abstract

Applications of massively parallel sequencing (MPS) in forensic genetics have allowed to exploit the true variation in core forensic STR loci, discover previously unknown STR alleles, aid mixture interpretation and will increase the statistical weight of the evidences. The worldwide populations database is exceedingly important in order to perform statistical calculations. In this study, we firstly present the population data for 27 autosomal STR loci of 148 Kinh ethnic individual living in Vietnam by using a MPS based on Illumina MiSeq platform. By using the largest number of markers for now, we indicated an increase in number of detected alleles as well. The combined match probability and power of exclusion reached 4.02E-30 and 0.999999999955384, respectively. The used markers are also demonstrated valuable in ancestry tracking of different human origins.

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Funding

This study was financially supported by the National Key Laboratory of Gene Technology, VAST.

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Authors and Affiliations

  1. Institute of Biotechnology, Vietnam Academy of Science and Technology, Cau Giay, 10000, Hanoi, Vietnam

    N. S. Pham, H. L. Tran, T. H. T. Nguyen, H. Hoang, Q. N. Tung & Q. T. Phi

  2. Graduate University of Science and Technology, Vietnam Academy of Science and Technology, Cau Giay, 10000, Hanoi, Vietnam

    N. S. Pham & Q. T. Phi

  3. Institute of Forensic Science, Ministry of Public Security, 10000, Nguyen Tuan, Thanh Xuan, Hanoi, Vietnam

    N. S. Pham & V. H. Nguyen

Authors
  1. N. S. Pham
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  2. H. L. Tran
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  3. T. H. T. Nguyen
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  4. V. H. Nguyen
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  5. H. Hoang
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  6. Q. N. Tung
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  7. Q. T. Phi
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Corresponding authors

Correspondence to T. H. T. Nguyen, V. H. Nguyen or Q. T. Phi.

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Conflict of interest. The authors declare that they have no conflict of interest.

Statement of compliance with standards of research involving humans as subjects. All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants involved in the study.

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Pham, N.S., Tran, H.L., Nguyen, T.H. et al. The First Autosomal STR Population Data of Kinh Ethinic Group in Vietnam by Using Massively Parallel Sequencing. Russ J Genet 57, 985–988 (2021). https://doi.org/10.1134/S102279542108010X

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  • DOI: https://doi.org/10.1134/S102279542108010X

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