1984 Volume 26 Issue 6 Pages 833-839
The biopsy specimens obtained by conventional bite biopsy technique are too small and too superficial in many cases. To conqure this deficit of the bite biopsy technique, we developed a new biopsy technique under direct visual control called strip-off biopsy. The method of this strip-off is following. Under fiberoptic observation, we injected saline around the aimed lesion and made a mucosal elevation. Then, the elevation was resected by electro-coagulation. After resection we removed the specimen by grasp forceps. According to this strip-off biopsy technique, we could remove specimens abuot 3 cm in length even the lesion was flat or depressed. We succeeded in total resection of a specimen of group 3 atypical mucosa and could easily demonstrated RLH of which main lesion located in the submucosal layer. Endoscopic observation revealed that the ulcer made by this procedure healed whithin 1-2 weeks. Obvious side effects such as bleeding and pain were not observed.