Applicability of high tube voltage imaging to achieve accurate quantitative images when applying photon counting detectors to general radiography

Rina Nishigami; Hiroaki Hayashi; Daiki Kobayashi; Tatsuya Maeda; Takashi Asahara; Yuki Kanazawa; Natsumi Kimoto; Shuichiro Yamamoto

doi:10.1117/12.3004150

1 April 2024 Applicability of high tube voltage imaging to achieve accurate quantitative images when applying photon counting detectors to general radiography

Rina Nishigami, Hiroaki Hayashi, Daiki Kobayashi, Tatsuya Maeda, Takashi Asahara, Yuki Kanazawa, Natsumi Kimoto, Shuichiro Yamamoto

Author Affiliations +

Proceedings Volume 12925, Medical Imaging 2024: Physics of Medical Imaging; 129252M (2024) https://doi.org/10.1117/12.3004150
Event: SPIE Medical Imaging, 2024, San Diego, California, United States

Conference Poster

Abstract

Energy-resolving photon counting detectors (ERPCDs) used for medical X-ray diagnosis have the potential to extract quantitative information concerning various organs. Previously, we proposed an analysis procedure to determine the effective atomic number (Z_eff), but parameter optimization is required. The purpose of this study is to develop an imaging simulator and to derive optimal imaging conditions. First, we created an imaging simulator taking into consideration the following three elements: (1) X-ray attenuation in objects, (2) detector response of cadmium zinc telluride (CZT), and (3) statistical fluctuation. Second, virtual phantoms consisting of soft tissue (Z_eff=6.5) and bone (Z_eff=13) with mass thicknesses (ρt) of 0.1 to 80g/cm² were made, and the Z_eff images were generated under various imaging conditions related to tube voltages (60 to 120kV) and energy bin settings (10keV intervals). Then, the optimal imaging condition was derived from the accuracy analysis of Z_eff images. Furthermore, a demonstration of clinical quantitative images was performed by using digital phantom which was created from voxel data of the CT image of human body phantom. The optimized imaging conditions were a tube voltage of 120kV with energy bin settings of 20–30–50–120keV. The applicable thickness ranges (achieving differences of +/- 1.0 from theoretical Z_effvalues) for Z_eff=13 and 6.5 were ρt=0.8 to 10g/cm² and 2 to 20g/cm², respectively. Using the above imaging conditions, we succeeded in generating accurate quantitative images of the pelvic region.

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

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Rina Nishigami, Hiroaki Hayashi, Daiki Kobayashi, Tatsuya Maeda, Takashi Asahara, Yuki Kanazawa, Natsumi Kimoto, and Shuichiro Yamamoto "Applicability of high tube voltage imaging to achieve accurate quantitative images when applying photon counting detectors to general radiography", Proc. SPIE 12925, Medical Imaging 2024: Physics of Medical Imaging, 129252M (1 April 2024); https://doi.org/10.1117/12.3004150

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