Improving objective measurements of the tumour-stroma ratio in breast cancer using polarized light microscopy

Jillian Sprenger; Ciara Murray; Jigar Lad; Blake Jones; Georgia Thomas; Sharon Nofech-Mozes; Mohammadali Khorasani; Alex Vitkin

doi:10.1117/12.2615729

7 December 2021 Improving objective measurements of the tumour-stroma ratio in breast cancer using polarized light microscopy

Jillian Sprenger, Ciara Murray, Jigar Lad, Blake Jones, Georgia Thomas, Sharon Nofech-Mozes, Mohammadali Khorasani, Alex Vitkin

Author Affiliations +

Proceedings Volume 11922, Advances in Microscopic Imaging III; 119220T (2021) https://doi.org/10.1117/12.2615729
Event: European Conferences on Biomedical Optics, 2021, Online Only

Abstract

Polarized light microscopy can be used to objectively quantify tumour-stroma ratio (TSR), a prognostic indicator validated in several cancers. Polarimetric results correctly differentiated between high- and low-stroma samples, and future work holds promise for improved separation.

Citation Download Citation

Jillian Sprenger, Ciara Murray, Jigar Lad, Blake Jones, Georgia Thomas, Sharon Nofech-Mozes, Mohammadali Khorasani, and Alex Vitkin "Improving objective measurements of the tumour-stroma ratio in breast cancer using polarized light microscopy", Proc. SPIE 11922, Advances in Microscopic Imaging III, 119220T (7 December 2021); https://doi.org/10.1117/12.2615729

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