1986 Volume 60 Issue 8 Pages 829-833
The records of 51 fungemia in aged patients at Tokyo Metropolitan Geriatric Hospital from 1972 through 1985 were reviewed. All cases were monomicrobial fungemia. Major funji isolated from the blood were Candida albicans (33.3%), Candida tropicalis (27.5%), and Candida glabrata (23.5%). Ninety eight per cent of them were Candida species. The predominant risk factors associated with fungemia were prior antibiotic therapy (88.2%), Foley catheter (64.7%), intravenous catheter (47.1%), anti cancer therapy (11.8%), adrenal corticosteroid administration (7.8%), and irradiation (5.9%). Major underlying diseases were longstanding bedridden state associated with cerebrovascular diseases (13 cases, 25.5%), solid tumor (14 cases, 27.5%), and haematological malignancies (4 cases, 7.8%). Tissue invasion by Candida albicans was found in two of 28 patients who died within a month after the isolation. The overall mortality rate was 61%.