Hepatitis induced by ECHO 6 virus were investigated with 6-week-old BABL/C mice, serum frompatients of aseptic meningitis and the following results were obtained.
1. Serum transaminase activity from patients of aseptic meningitis due to ECHO 6 were slightlyraised.
2. Serum transaminase activity from mice which were inoculated intraperitoneal with prototypeof ECHO 6, 6′, 6′′ and wild type of ECHO 6 virus were slightly raised and rate of hepatitis were16-43%.
3. On histopathological research, hepatitis due to ECHO 6, 6′, 6′′ virus were recognized.