Hostname: page-component-848d4c4894-p2v8j Total loading time: 0.001 Render date: 2024-05-20T13:41:46.358Z Has data issue: false hasContentIssue false

The Human Genome as Common Heritage: Common Sense or Legal Nonsense?

Published online by Cambridge University Press:  01 January 2021

Extract

In the opening years of the 21st century, it became fashionable to describe the human genome as belonging to the common heritage of humanity. The United Nations, in its Universal Declaration on the Human Genome and Human Rights, now identifies the human genome as part of the common heritage, as does the international Human Genome Organization (HUGO) and the Council of Europe. The common heritage concept has played a prominent role in arguments against patenting the human genome or portions thereof. This essay considers whether the common heritage designation will advance the political and legal goals of its proponents.

Type
Symposium
Copyright
Copyright © American Society of Law, Medicine and Ethics 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Aguis, E., “Germ-Line Cells – Our Responsibilities for Future Generations,” in Busuttil, S. et al., eds., Our Responsibilities towards Future Generations (Valletta, Malta: Foundation for International Studies, 1990): 133143.Google Scholar
Curien, H., “The Human Genome Project and Patents,” Science 254, no. 5039 (1991): 17101712.Google Scholar
Knoppers, B. M., “Biobanking: International Norms,” Journal of Law, Medicine & Ethics 33, no. 1 (2005): 714, at 11 (“At the international level, there is increasing recognition and confirmation that, at the level of species, the human genome is the common heritage of humanity, and that human genetic research databases are global public goods.”)CrossRefGoogle Scholar
UNESCO, “Universal Declaration on the Human Genome and Human Rights,” Resolution 152, United Nations General Assembly, 53rd Session, U.N. Doc. A/53/635/Add.2, 1998, available at <http://portal.unesco.org/en/ev.php-URL_ID=13177&URL_D0=D0_T0PIC&URL_SECTI0N=201.html> (last visited June 26, 2007), reprinted in Lenoir, N., “Universal Declaration on the Human Genome and Human Rights: The First Legal and Ethical Framework at the Global Level,” Columbia Human Rights Law Review (1999): 537-587.Google Scholar
The Human Genome Organization, “Statement on the Principled Conduct of Genetics Research,” Eubios Journal of Asian and International Bioethics 6, no. 3 (1996): 5960; The Human Genome Organization, Statement on Benefit Sharing, April 9, 2000, available at <http://www.hugo-international.org/Statement_on_Benefit_Sharing.htm> (last visited June 19, 2007) [hereinafter cited as Benefit Sharing]; Council of Europe (Parliamentary Assembly), Recommendation 1512, Protection of the Human Genome by the Council of Europe, 2001, available at <http://assembly.coe.int/Documents/AdoptedText/ta01/erec1512.htm> (last visited June 25, 2007).+(last+visited+June+19,+2007)+[hereinafter+cited+as+Benefit+Sharing];+Council+of+Europe+(Parliamentary+Assembly),+Recommendation+1512,+Protection+of+the+Human+Genome+by+the+Council+of+Europe,+2001,+available+at++(last+visited+June+25,+2007).>Google Scholar
See, e.g., Sturges, M. L., “Who Should Hold Property Rights to the Human Genome? An Application of the Common Heritage of Humankind,” American University International Law Review 13 (1997): 219261; see Curien, , supra note 2; Demaine, L. J. and Fellmeth, A. X., “Reinventing the Double Helix: A Novel and Nonobvious Reconceptualization of the Biotechnology Patent,” Stanford Law Review 55 (2002): 303-462, at 442: “Scores of eminent scientists and many foreign governments have taken the position that the human genome and other naturally occurring genomes are res communis – the common heritage and inheritance of mankind – and, therefore, should not be subject to patents”; Karjala, D. S., “Biotech Patents and Indigenous Peoples,” Minnesota Journal of Law, Science & Technology 7 (2006): 483-527.Google Scholar
Rose, C. M., “The Comedy of the Commons: Custom, Commerce, and Inherently Public Property,” University of Chicago Law Review 53, no. 3 (1986): 711781; Rose, C. M., “Takings, Public Trust, Unhappy Truths, and Helpless Giants: A Review of Professor Joseph Sax's Defense of the Environment through Academic Scholarship: Joseph Sax and the Idea of Public Trust,” Ecology Law Quarterly 25 (1998): 351-362.CrossRefGoogle Scholar
These categories derive from ancient Roman law. Bovenberg, J. A., “Mining the Common Heritage of Our DNA: Lessons Learned from Grotius and Pardo,” Duke Law & Technology Review 8 (2006): Paragraphs 9–12, available at <http://www.law.duke.edu/journals/dltr/articles/2006dltr0008.html> (last visited June 25, 2007).Google Scholar
United Nations, “Convention on the Law of the Sea,” U.N. Document A/Conf.62/122, reprinted in International Legal Materials Treaties and Agreements 21 (1982): 12611354.CrossRefGoogle Scholar
See Rose, (1998), supra note 7.Google Scholar
Sax, J. L., “The Public Trust Doctrine in Natural Resource Law: Effective Judicial Intervention,” Michigan Law Review 68 (1970): 471566.CrossRefGoogle Scholar
Id.; see also Rose, (1998), supra note 7.Google Scholar
Res publicae referred to streams and ports. See Bovenberg, , supra note 8, at paragraph 9; see also, National Audubon Society et al. v. Dept. of Water and Power of the City of Los Angeles, 33 Cal. 3d 419 (1983) (en banc, rehearing denied) (“‘By the law of nature these things are common to mankind – the air, running water, the sea and consequently the shores of the sea.’ [Institutes of Justinian 2.1.1.] From this origin in Roman law, the English common law evolved the concept of the public trust, under which the sovereign owns ‘all of its navigable waterways and the lands lying beneath them as trustee of a public trust for the benefit of the people,’” at 433–434) [hereinafter cited as National Audubon Society].Google Scholar
Id. (National Audubon Society).Google Scholar
See Friends of Van Cortlandt Park v. City of New York, 95 N.Y.2d 623 (2001).Google Scholar
See Sax, , supra note 11.Google Scholar
Id.; see also National Audubon Society, supra note 13, at 438439.Google Scholar
See Rose, (1986), supra note 7; Sax, supra note 11.Google Scholar
Baslar, K., The Concept of the Common Heritage of Mankind in International Law (The Hague/Boston/London: Martinus Nijhoff, 1998): at 85–91.Google Scholar
Looney, B., “Should Genes Be Patented? The Gene Patenting Controversy: Ethical and Policy Foundations of an International Agreement,” Law and Policy in International Business 26 (1994): 231272.Google Scholar
Reviewed in Baslar, , supra note 20, at 108–109, chap. 5, 6, and 7.Google Scholar
To some degree, the distinction between the CHPD and the CHDD correlates with a distinction made by Baslar between the CH as applied to lands and resources found in extranational spaces (places beyond national boundaries, such as the deep sea or the moon) and the CH as applied to lands and resources found within the boundaries of sovereign states. See Baslar, , supra note 20, at 110–111, chap. 8.Google Scholar
See Convention on the Law of the Sea, supra note 9.Google Scholar
The Antarctica Treaty System includes the Antarctic Treaty of 1969, measures enacted under the 1969 treaty, and associated multilateral and bilateral instruments. See Baslar, , supra note 20, at chap. 7; United Nations, Agreement Governing the Activities of States on the Moon and Other Celestial Bodies – U.N. Doc. A/AC.105/L.113/Add. 4, reprinted in Houston International Law Journal 2, no. 3 (1979): 333.Google Scholar
Reynolds, G. H. and Merges, R. P., Outer Space: Problems of Law and Policy (San Francisco: Westview Press, 1989); Vernon, C. M., “Common Cultural Property: The Search for Rights of Protective Intervention,” Case Western Reserve Journal of International Law 26 (1994): 435-478.Google Scholar
The first use of the “common heritage” concept in a contemporary legal context is attributed to Arvid Pardo, a Maltese Ambassador to the United Nations, who used the term in an address on deep sea mining before the United Nations General Assembly in 1967. See Baslar, , supra note 20, at 3137.Google Scholar
Shiva, V., “Biotechnology Development and the Conservation of Biodiversity,” in Shiva, V. and Moser, I., eds., Biopolitics: A Feminist and Ecological Reader on Biotechnology (London and New Jersey: Zed Books, 1995): 193213; see Reynolds, , Merges, , supra note 26, at 7.Google Scholar
For an extensive review of the economic arguments and excerpts from the literature, see Reynolds, and Merges, , supra note 26.Google Scholar
See Convention on the Law of the Sea, supra note 9.Google Scholar
See Baslar, , supra note 20, at 206.Google Scholar
Convention on the Law of the Sea, supra note 9, at Article 140.Google Scholar
Id., at Article 140, 144, 150.Google Scholar
Id., at Article 156, 159.Google Scholar
Hardin, G., “The Tragedy of the Commons,” Science 162, no. 3859 (1968): 12431248.Google Scholar
See Reynolds, and Merges, , supra note 26.Google Scholar
See, e.g., Harry, D. et al., Declaration of Indigenous Peoples of the Western Hemisphere Regarding the Human Genome Diversity Project, signed by 18 organizations on February 19, 1995, available at <http://ankn.uaf.edu/IKS/declaration.html> (last visited June 29, 2007); Crieger, B. J., “The West Knows Best?” The Hastings Center Report 26, no. 2 (1996): 50; see Shiva, , supra note 28; Whitt, L. A., Biocolonialism and the Commidification of Knowledge, paper prepared for the North American Conference on Genetic Research and Native Peoples: Colonialism through Biopiracy, 1998 (paper on file with author); Reardon, J., “The Human Genome Diversity Project: A Case Study in Coproduction,” Social Studies of Science 31, no. 3 (2001): 357-388; Rohter, L., “In the Amazon, Giving Blood But Getting Nothing,” New York Times National Edition, June 20, 2007, at A1.Google Scholar
See, e.g., Tokar, B., The Human Genome Diversity Project: Indgenous Communities and the Commercialization of Science (Plainfield, Canada: The Edmonds Institute, 1998).Google Scholar
Discussed in Karjala, , supra note 6.Google Scholar
A problem with the one-country-one-vote model is that it provides a mechanism for ratifying the interests of national governments, but it does not necessarily provide a mechanism for identifying or responding to the interests of minority groups within nation states. In designing a governance structure, one ought not to expect that national governments are equally effective at representing the interests of all people within their jurisdictions. Furthermore, some indigenous communities have a sovereign or quasi-sovereign status within larger nation-states, and it is not clear that governments of nation-states can or ought to represent these indigenous communities. How would American Indian tribes be represented in the governance of a CH property?.Google Scholar
A related solution has been suggested by Bovenberg, supra note 8, at paragraph 31.Google Scholar
See Vernon, , supra note 26; Shiva, , supra note 28; id.Google Scholar
Juengst, E. T., “Should We Treat the Human Germ-Line as a Global Human Resource?” in Agius, E., Busuttil, S., eds., Germ-Line Intervention and Our Responsibilities to Future Generations (Great Britain: Kluwer Academic Press, 1998): 85102.CrossRefGoogle Scholar
See Convention on the Law of the Sea, supra note 9.Google Scholar
Merryman, J. H., “Two Ways of Thinking About Cultural Property,” American Journal of International Law 80 (1986): 831853; Sax, J. L., “Is Anyone Minding Stonehenge? The Origins of Cultural Property Protection in England,” California Law Review 78 (1990): 1543–1567 [hereinafter cited as Stonehenge]; Sax, J. L., “Heritage Preservation as a Public Duty: The Abbe Gregoire and the Origins of an Idea,” Michigan Law Review 88 (1990): 1142-1168.CrossRefGoogle Scholar
United Nations, “Convention Concerning the Protection of the World Cultural and Natural Heritage,” U.S. Treaties and Other International Agreements, Paris, 1972 [hereinafter cited as World Heritage Convention]; UNESCO, “Convention for the Protection of Cultural Property in the Event of Armed Conflict,” United Nations Treaties Series 249 (1954): 215–240, available at <http://untreaty.un.org/English/acess.asp> (last visited June 12, 2007). As of May 2005, there were 114 states party to this Convention; the United States signed in May 1954, and the treaty was submitted to the U.S. Senate on January 6, 1999, as Treaty Doc. 106–1. To date, the Senate has not held any hearings on this Treaty. Discussed in Hagen, P. E., “Treaty Priority List for the 110th Congress,” American Law Institute – American Bar Association Continuing Legal Education SM 083 (2007): 189-197, at 192.+(last+visited+June+12,+2007).+As+of+May+2005,+there+were+114+states+party+to+this+Convention;+the+United+States+signed+in+May+1954,+and+the+treaty+was+submitted+to+the+U.S.+Senate+on+January+6,+1999,+as+Treaty+Doc.+106–1.+To+date,+the+Senate+has+not+held+any+hearings+on+this+Treaty.+Discussed+in+Hagen,+P.+E.,+“Treaty+Priority+List+for+the+110th+Congress,”+American+Law+Institute+–+American+Bar+Association+Continuing+Legal+Education+SM+083+(2007):+189-197,+at+192.>Google Scholar
Id. (1954 Convention).Google Scholar
See World Heritage Convention, supra note 46.Google Scholar
See Baslar, , supra note 20, at 117–158.Google Scholar
See World Heritage Convention, supra note 46.Google Scholar
See Baslar, , supra note 20, at 117–158.Google Scholar
See Merryman, , supra note 45; Sax (Stonehenge), supra note 45.Google Scholar
ASHG Statement, “Professional Disclosure of Familial Information,” American Journal of Human Genetics 62, no. 3 (1998): 474483.CrossRefGoogle Scholar
See, e.g., Dennis, C., “The Rough Guide to the Genome,” Nature 425, no. 6960 (2003): 758759; The Human Genome Structural Variation Working Group, “Completing the Map of Human Genetic Variation,” Nature 447, no. 7141 (2007): 161–165; Ossorio, P. N., “About Face: Forensic Genetic Testing for Race and Other Visible Traits,” Journal of Law, Medicine & Ethics 34, no. 2 (2006): 277–292; Smith, M. W. and Patterson, N. et al., “A High Density Admixture Map for Disease Gene Discovery in African Americans,” American Journal of Human Genetics 74, no. 5 (2004): 1001-1013; Kittles, R. A., Weiss, K. M., “Race, Ancestry, and Genes: Implications for Defining Disease Risk,” Annual Review of Genomics and Human Genetics 4 (2003): 33-67.CrossRefGoogle Scholar
Council of Europe, Texts Adopted, Recommendation 934 on Genetic Engineering, P.A. 33rd Sess., Pt. III, 1982, available at <http://assmbly.coe.int/Main.asp?link=/Documents/AdoptedText/ta82/EREC934.htm> (last visited June 12, 2007) (recommendation 4.a.'the rights to life and human dignity protected by Articles 2 and 3 of the European Convention on Human Rights imply the right to inherit a genetic pattern which has not been artificially changed.”)+(last+visited+June+12,+2007)+(recommendation+4.a.'the+rights+to+life+and+human+dignity+protected+by+Articles+2+and+3+of+the+European+Convention+on+Human+Rights+imply+the+right+to+inherit+a+genetic+pattern+which+has+not+been+artificially+changed.”)>Google Scholar
See Juengst, , supra note 43.Google Scholar
International Human Genome Sequencing Consortium, “Finishing the Euchromatic Sequence of the Human Genome,” Nature 431, no. 7011 (2004): 931945; Cook-Deegan, R., The Gene Wars: Science, Politics, and the Human Genome (New York: W. W. Norton, 1994); Kevles, D. J. and Hood, L., eds., The Code of Codes: Scientific and Social Issues in the Human Genome Project (Cambridge: Harvard University Press, 1992).Google Scholar
See Sturges, , supra note 6, at 224.Google Scholar
See Juengst, , supra note 43.Google Scholar
Barton, N. H. and Charlesworth, B., “Why Sex and Recombination,” Science 281, no. 5385 (1998): 19861989.CrossRefGoogle Scholar
Neel, J. V., Physician to the Gene Pool: Genetic Lessons and Other Stories (New York: James Wiley & Sons, Inc., 1994).Google Scholar
See Council of Europe, supra note 55; Knoppers, B. M., Human Dignity and Genetic Heritage (Ottowa: Law Reform Commission of Canada, 1991): at 93.Google Scholar
Ossorio, P. N., “Legal and Ethical Issues in Biotechnology Patenting,” in Burley, J. and Harris, J., eds., A Companion to Genethics: Philosophy and the Genetic Revolution (Oxford: Blackwell Publishers, Ltd., 2002): 408419.Google Scholar
“Contents and term of patent,” United States Code, Title 35, section 154 (a)(1) (2007) (“Every patent shall contain a short title of the invention and a grant to the patentee., of the right to exclude others from making, using offering for sale, or selling the invention throughout the United States or importing the invention into the united states.”)Google Scholar
See Ossorio, , supra note 63.Google Scholar
This approach would be similar to the march-in right currently granted under U.S. law to federal agencies that fund research resulting in patented inventions. “March-in rights,” United States Code, Title 35, Chapter 18, section 203 (2007). No federal agency has ever exercised the march-in right.Google Scholar
This approach bears some relation to proposals that biobanks should act as trustees for individuals whose samples and information are included in the bank. See Winickoff, D. E. and Winickoff, R. N., “The Charitable Trust as a Model for Genomic Biobanks,” New England Journal of Medicine 349, no. 12 (2003): 11801184.CrossRefGoogle Scholar
For proposals for sharing the benefits of biomedical research through taxation see, see Bovenberg, , supra note 8, at paragraph 31; Sharing, Benefit, supra note 5; Bovenberg, J. A., “Whose Tissue Is It Anyway?” Nature Biotechnology 23, no. 8 (2005): 929933.CrossRefGoogle Scholar
See Bovenberg, , supra note 8, at paragraph 29.Google Scholar
Heller, M. A. and Eisenberg, R. S., “Can Patents Deter Innovation? The Anticommons in Biomedical Research,” Science 280, no. 5377 (1998): 698701; Eisenberg, R. S., “Patents and the Progress of Science: Exclusive Rights and Experimental Use,” University of Chicago Law Review 56 (1993): 1017-1086.CrossRefGoogle Scholar
Hettinger, N., “Patenting Life: Biotechnology, Intellectual Property, and Environmental Ethics,” Boston College Environmental Affairs Law Review 22 (1995): 267304.Google Scholar
Cornes, R. and Sandler, T., The Theory of Externalities, Public Goods, and Club Goods (New York: Cambridge University Press, 1986).Google Scholar
Note, however, that patents do not necessarily create true economic monopolies. If products not covered by the patent can compete in the same market as the patented item, and the patentee cannot control pricing in that market, then the patent has not conferred a true monopoly. Numerous patented drugs, such as cholesterol lowering statins, have sold in markets in which several different patented drugs, or various patented and unpatented drugs, competed.Google Scholar
“Contents and Term of Patent,” United States Code, Title 35, section 154 (a)(2) (2007) (“such grant shall be for a term beginning on the date on which the patent issues and ending 20 years from the date on which the application for the patent was filed in the United States…”). Determining the actual date on which a patent expires is not always straightforward. The date of filing can be earlier than the date of the application on which the patent issues, and there are statutory provisions that allow for the terms of some patents to be extended.Google Scholar