ORIGINAL ARTICLEMicrovasculature partial endothelial mesenchymal transition in early posttransplant biopsy with acute tubular necrosis identifies poor recovery renal allografts
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KEYWORDS
biomarker
clinical research / practice
delayed graft function (DGF)
ischemia/reperfusion injury (IRI)
kidney transplantation/nephrology
pathology/histopathology
rejection: antibody-mediated (ABMR)
translational research/science
vascular biology
Abbreviations
ABMR
antibody-mediated rejection
ATN
acute tubular necrosis
DGF
delayed graft function
DSA
donor-specific antibodies
eGFR
estimated glomerular filtration rate
EndMT
endothelial to mesenchymal transition
I/R
ischemia/reperfusion
IF/TA
interstitial fibrosis and tubular atrophy
KIM-1
kidney injury molecule-1
MFI
mean fluorescence intensity
pEMT
partial epithelial to mesenchymal transition
pEndMT
partial endothelial to mesenchymal transition
TGFβ1
transforming growth factor-β1
TNFα
tumor necrosis factor α
αSMA,
α smooth muscle actin
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Yi-Chun Xu-Dubois and Pedram Ahmadpoor contributed equally to this article.
Copyright © 2020 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights reserved. Published by Elsevier B.V. All rights reserved.