Relaxation dynamics of a single DNA molecule

E. Goshen, W. Z. Zhao, G. Carmon, S. Rosen, R. Granek, and M. Feingold

Phys. Rev. E 71, 061920 – Published 28 June 2005

Abstract

The relaxation of a single DNA molecule is studied. The experimental system consists of optical tweezers and a micron-sized bead that is tethered to the bottom of the sample by a single double-stranded DNA molecule. The bead slows down the DNA relaxation from a strongly stretched configuration such that it is passing through stretched equilibrium states. This allows for a theoretical description of the relaxation trajectory, which is in good agreement with experiment.

Received 3 February 2005

DOI:https://doi.org/10.1103/PhysRevE.71.061920

Authors & Affiliations

E. Goshen¹, W. Z. Zhao^1,3, G. Carmon¹, S. Rosen¹, R. Granek², and M. Feingold¹

¹Department of Physics and The Ilse Katz Center for Nanotechnology, Ben Gurion University, Beer Sheva 84105, Israel
²Department of Biotechnology Engineering and Institute for Applied Biosciences, Ben Gurion University, Beer Sheva 84105, Israel
³Department of Mathematics, Capital Normal University, Beijing 100037, China

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Issue

Vol. 71, Iss. 6 — June 2005

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Physical Review E

covering statistical, nonlinear, biological, and soft matter physics