Germ Line Specificity of P-element Transposition and Some Novel Patterns of Expression of Transduced Copies of the white Gene
This extract was created in the absence of an abstract.
Excerpt
P TRANSPOSABLE ELEMENTS
P clements, the family of mobile genetic elements that are responsible for the phenomenon of P-M hybrid dysgenesis in Drosophila melanogaster, are of particular interest because their mobility has been shown to be under genetic control (for reviews, see Bregliano and Kidwell 1983; Engels 1983). When the elements are quiescent they are said to be in the P cytotype (Engels 1979a), the cellular environment of P-strain flies. P cytotype is apparently determined by the P factors themselves (Engels 1979b). P factors, which are defined by genetic assays, are presumed to correspond to a fully functional subset of the biochemically defined P elements (O'Hare and Rubin 1983). Flies lacking functional P elements are called M-strain flies, and are said to possess the M cytotype. Hybrid dysgenesis occurs when P-strain males are crossed to M-strain females, thereby introducing functional P elements into the M cytotype. The offspring of such...
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↵* Present address: Department of Biochemistry, Imperial College of Science and Technology, London SW72AZ, England.
