Clinical InvestigationPrevalence and Molecular Characterization of Dengue Viruses Serotypes in 2010 Epidemic
Section snippets
Sample Collection
In the current clinical study, a total of 317 serum samples were obtained from suspected individuals of Lahore, Sheikhpura and Gujranwala cities of Pakistan between August and November 2010 showing symptoms of headache, fever, rash, bleeding, myalgia and arthralgia and consistent temperature above 38°C. The patients were divided into 2 categories: patients having DF without hemorrhagic manifestations (n=228) and patients having DF with hemorrhagic manifestations based on clinical symptoms
RESULTS
In this study, a total of 317 serum samples were included and divided into 2 main groups: patients having DF without hemorrhagic manifestations (DF) (n=228) and patients having DF with hemorrhagic manifestation symptoms (DHF) (n=89) and evaluated further for parameters as described in Table 1. Fever (temperature > 38°C), headache, myalgia and decreased platelet counts were observed in almost all cases; however, these conditions were more severe in patients having DF with hemorrhagic
DISCUSSION
A total of 317 patients were included in this study and divided into 2 groups: patients having DF without hemorrhagic manifestations (DF) (n=228) and patients having DF with hemorrhagic manifestation symptoms (DHF) (n=89). The patients were initially diagnosed by general clinical symptoms and blood analysis, which include platelet count, leukocyte count and hematocrit percentage, which were disturbed frequently in most of the cases in DF and DHF groups.
The patients of both DF and DHF categories
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