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Prevalence of and Risk Factors for Vancomycin-Resistant Staphylococcus aureus Precursor Organisms in Southeastern Michigan

Published online by Cambridge University Press:  10 May 2016

Valerie S. Albrecht ,
Marcus J. Zervos ,
Keith S. Kaye ,
Pritish K. Tosh ,
Samia Arshad ,
Kayoko Hayakawa ,
Alexander J. Kallen ,
Linda K. McDougal ,
Brandi M. Limbago  and
Alice Y. Guh
Valerie S. Albrecht
Affiliation:
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia
Marcus J. Zervos
Affiliation:
Division of Infectious Diseases, Henry Ford Health System, Detroit, Michigan
Keith S. Kaye
Affiliation:
Division of Infectious Diseases, Detroit Medical Center, Detroit, Michigan
Pritish K. Tosh
Affiliation:
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia; and Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota
Samia Arshad
Affiliation:
Division of Infectious Diseases, Henry Ford Health System, Detroit, Michigan
Kayoko Hayakawa
Affiliation:
Division of Infectious Diseases, Detroit Medical Center, Detroit, Michigan
Alexander J. Kallen
Affiliation:
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia
Linda K. McDougal
Affiliation:
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia
Brandi M. Limbago
Affiliation:
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia
Alice Y. Guh*
Affiliation:
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia
*
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30329 (ggt4@cdc.gov).
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Abstract

We assessed for vancomycin-resistant Staphylococcus aureus (VRSA) precursor organisms in southeastern Michigan, an area known to have VRSA. The prevalence was 2.5% (pSK41-positive methicillin-resistant S. aureus, 2009–2011) and 1.5% (Inc18-positive vancomycin-resistant Enterococcus, 2006–2013); Inc18 prevalence significantly decreased after 2009 (3.7% to 0.82%). Risk factors for pSK41 included intravenous vancomycin exposure.

Infect Control Hosp Epidemiol 2014;35(12):1531–1534

Type
Brief Report
Information
Infection Control & Hospital Epidemiology , Volume 35 , Issue 12 , December 2014 , pp. 1531 - 1534
Copyright
© 2014 by The Society for Healthcare Epidemiology of America. All rights reserved.

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References

1. Limbago, BM, Kallen, AJ, Zhu, W, Eggers, P, McDougal, LK, Albrecht, VS. Report of the 13th vancomycin-resistant Staphylococcus aureus isolate from the United States. J Clin Microbiol 2014;52:998–1002.Google Scholar
2. Centers for Disease Control and Prevention (CDC). CDC reminds clinical laboratories and healthcare infection preventionists of their role in the search and containment of vancomycin-resistant Staphylococcus aureus (VRSA). http://www.cdc.gov/HAI/settings/lab/vrsa_lab_search_containment.html. Accessed August 2, 2014.Google Scholar
3. Zhu, W, Clark, N, Patel, JB. pSK41-like plasmid is necessary for Inc18-like vanA plasmid transfer from Enterococcus faecalis to Staphylococcus aureus in vitro. Antimicrob Agents Chemother 2013;57:212–219.Google Scholar
4. Zhu, W, Murray, PR, Huskins, WC, et al. Dissemination of an Enterococcus Inc18-like vanA plasmid associated with vancomycin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 2010;54:4314–4320.CrossRefGoogle ScholarPubMed
5. Tosh, PK, Agolory, S, Strong, BL, et al. Prevalence and risk factors associated with vancomycin-resistant Staphylococcus aureus precursor organism colonization among patients with chronic lower-extremity wounds in southeastern Michigan. Infect Control Hosp Epidemiol 2013;34:954–960.Google Scholar
6. McDougal, LK, Fosheim, GE, Nicholson, A, et al. Emergence of resistance among USA300 methicillin-resistant Staphylococcus aureus isolates causing invasive disease in the United States. Antimicrob Agents Chemother 2010;54:3804–3811.Google Scholar
7. Reyes, K, Malik, R, Moore, C, Donabedian, S, Perri, M, Johnson, L, Zervos, M. Evaluation of risk factors for coinfection or cocolonization with vancomycin-resistant enterococcus and methicillin-resistant Staphylococcus aureus. J Clin Microbiol 2010;48:628–630.Google Scholar
8. Melo-Cristino, J, Resina, C, Manuel, V, Lito, L, Ramirez, M. First case of infection with vancomycin-resistant Staphylococcus aureus in Europe. Lancet 2013;382(9888):205.Google Scholar
9. Rossi, F, Diaz, L, Wollam, A, et al. Transferable vancomycin resistance in a community-associated MRSA lineage. N Engl J Med 2014;370(16):1524–1531.Google Scholar