Journal of Biological Chemistry
Volume 285, Issue 30, 23 July 2010, Pages 22864-22873
Signal TransductionActivation of Swelling-activated Chloride Current by Tumor Necrosis Factor-α Requires ClC-3-dependent Endosomal Reactive Oxygen Production*
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Chloride Channels
Chloride Transport
Reactive Oxygen Species (ROS)
Thrombin
Tumor Necrosis Factor (TNF)
Chloride-Proton Antiporter
Swelling-activated Chloride Channel
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- *
This work was supported, in whole or in part, by National Institutes of Health Grants HL62483 (to F. S. L.), HL081750 (to F. J. M.), AI067533 (to J. G. M.), and DK07690-15 (to J. J. M.). This work was also supported by grants from the American Heart Association (to F. S. L.), and the Department of Veterans Affairs Office of Research and Development (to F. J. M.).
The on-line version of this article (available at http://www.jbc.org) contains supplemental Figs. 1 and 2.
© 2010 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.