Journal of Biological Chemistry
Cell BiologyCapping protein is dispensable for polarized actin network growth and actin-based motility
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Author contributions—M. A.-G., C. S., and J. P. conceptualization; M. A.-G., R. K., S. K., and J. P. formal analysis; M. A.-G. and J. P. validation; M. A.-G, R. K., S. K., J. M., and J. P. investigation; M. A.-G., R. K., and J. P. visualization; M. A.-G., R. K., S. K., J. M., and J. P. methodology; R. K. software; J. M. and J. F. resources; J. F., C. S., and J. P. writing-review and editing; C. S. and J. P. funding acquisition; J. P. supervision; J. P. writing-original draft; J. P. project administration.
Funding and additional information—This work was supported by grants from the program “Investissements d'Avenir” from the French Government and implemented by ANR Grants ANR-10-LABX-0038 and ANR-10-IDEX-0001-02 PSL and a post-Ph.D. grant (to M. A.-G.). J. P. was supported by Fondation pour la Recherche Médicale Grant DEQ20120323737 and Fondation ARC Grants PJA 20151203487 and PJA 20191209604. M. A.-G. was supported by a Ph.D. fellowship from La Ligue Contre le Cancer. S.K. was supported by the ERASMUS+ Student Mobility Placement program. R. K. was supported by the Bettencourt Schueller Foundation long-term partnership and partly by the CRI Research Fellowship program.
Conflict of interest—The authors declare that they have no conflicts of interest with the contents of this article.
Abbreviations—The abbreviations used are:
- CP
capping protein
- TIRF
total internal reflection fluorescence
- FAB
F-actin–binding protein
- GAB
G-actin–binding domain
- PP
polyproline
- TET
tetramerization
- GST
glutathione S-transferase.