Journal of Biological Chemistry
Volume 294, Issue 23, 7 June 2019, Pages 9186-9197
Cell BiologyThe histone demethylase JMJD2B is critical for p53-mediated autophagy and survival in Nutlin-treated cancer cells
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autophagy
p53
histone demethylase
mouse double minute 2 homolog (MDM2)
histone methylation
ATG16L1
ULK1
Jumonji domain containing protein 2B (JMJD2B)
nutlin
cancer
epigenetic regulation
chromatin regulation
MDM2 proto-oncogene
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This work was supported by National Cancer Institute, National Institutes of Health Grant 1 R21 CA185036–01A1 (to C. G. M) and by a Swim Across America Foundation Grant (to C. G. M). The authors declare that they have no conflicts of interest with the contents of this article. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
© 2019 Duan et al.