Journal of Biological Chemistry
Protein Structure and FoldingStructure of a High Fidelity DNA Polymerase Bound to a Benzo[a]pyrene Adduct That Blocks Replication*
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The atomic coordinates and structure factors (code 1XC9 ([BP]dG at the post-insertion site of BF)) have been deposited in the Protein Data Bank, Research Collaboratory for Structural Bioinformatics, Rutgers University, New Brunswick, NJ (http://www.rcsb.org/).
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This work was supported principally by the Offices of Biological and Environmental Research and Basic Energy Sciences of the United States Department of Energy and from the National Center for Research Resources of the National Institutes of Health. This work was also supported by National Institutes of Health Grants CA 099194 (to N. E. G.) and CA92584 (to L. S. B.) and by the Duke Comprehensive Cancer Center (L. S. B.). The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.