Journal of Biological Chemistry
Protein Structure and FoldingStructures of Argininosuccinate Synthetase in Enzyme-ATP Substrates and Enzyme-AMP Product Forms: STEREOCHEMISTRY OF THE CATALYTIC REACTION*
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The atomic coordinates and structure factors (code 1J1Z (ATP· citrulline·aspartate complex), 1J20 (AMP·argininosuccinate complex), and 1KH3 (AMP-PNP·arginine·asparate·MG2+ complex) have been deposited in the Protein Data Bank, Research Collaboratory for Structural Bioinformatics, Rutgers University, New Brunswick, NJ (http://www.rcsb.org/).
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This work was supported by Grant-in-aid for Scientific Research on Priority Area from the Ministry of Education, Science, Sports, and Culture of Japan B:13125207 (to K. H.) and by a Research Grant from the Japan Society for the Promotion of Science (Category B 13480196 (to K. H.)). The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.