Tick-borne encephalitis and its global importance
Gerhard Dobler
+ Author Affiliations
- Author Affiliations
A Bundeswehr Institute of Microbiology, Neuherbergstrasse 11
B Tel: +49 89 992692 3974
C Fax: +49 89 992692 3983
D Email: gerharddobler@bundeswehr.org
Microbiology Australia 39(4) 191-194 https://doi.org/10.1071/MA18061
Published: 24 October 2018
Abstract
Tick-borne encephalitis (TBE) is the most important tick-transmitted human viral disease in Europe and Asia with up to 10000 human cases annually. The etiologic agents of TBE are the three subtypes of tick-borne encephalitis virus (TBEV), a member of the genus Flavivirus in the family Flaviviridae. The Far-Eastern subtype and the Siberian subtype are both mainly transmitted by Ixodes persulcatus; the European subtype is mainly transmitted by Ixodes ricinus. Besides tick bite, TBEV can be transmitted by unpasteurised milk from goat, sheep and cattle during the viremic phase of infection by the oral route of infection (alimentary form of TBE). There is no treatment for TBE available, but there are effective and well tolerated vaccines against TBE, which are recommended for people living or travelling to endemic countries with a risk of infection.
References
[1] Bogovic, P. et al. (2015) Tick-borne encephalitis: a review of epidemiology, clinical characteristics, and management. World J. Clin. Cases 3, 430–441.| Tick-borne encephalitis: a review of epidemiology, clinical characteristics, and management.Crossref | GoogleScholarGoogle Scholar |
[2] Ecker, M. et al. (1999) Sequence analysis and genetic classification of tick-borne encephalitis viruses from Europe and Asia. J. Gen. Virol. 80, 179–185.
| Sequence analysis and genetic classification of tick-borne encephalitis viruses from Europe and Asia.Crossref | GoogleScholarGoogle Scholar |
[3] Kovalev, S.Y. et al. (2017) Reconsidering the classification of tick-borne encephalitis virus within the Siberian subtype gives new insights into its evolutionary history. Infect. Genet. Evol. 55, 159–165.
| Reconsidering the classification of tick-borne encephalitis virus within the Siberian subtype gives new insights into its evolutionary history.Crossref | GoogleScholarGoogle Scholar |
[4] Dai, X. et al. (2018) A new subtype of eastern tick-borne encephalitis virus discovered in Qinghai-Tibet Plateau, China. Emerg. Microbes Infect. 7, 74.
| A new subtype of eastern tick-borne encephalitis virus discovered in Qinghai-Tibet Plateau, China.Crossref | GoogleScholarGoogle Scholar |
[5] Heinze, D.M. et al. (2012) Revisiting the clinal concept of evolution and dispersal for the tick-borne flaviviruses by using phylogenetic and biogeographic analyses. J. Virol. 86, 8663–8671.
| Revisiting the clinal concept of evolution and dispersal for the tick-borne flaviviruses by using phylogenetic and biogeographic analyses.Crossref | GoogleScholarGoogle Scholar |
[6] Süss, J. (2008) Tick-borne encephalitis in Europe and beyond—the epidemiological situation as of 2007. Euro Surveill. 13, 18916.
| Tick-borne encephalitis in Europe and beyond—the epidemiological situation as of 2007.Crossref | GoogleScholarGoogle Scholar |
[7] Holzmann, H. et al. (2009) Tick-borne encephalitis from eating goat cheese in a mountain region of Austria. Emerg. Infect. Dis. 15, 1671–1673.
| Tick-borne encephalitis from eating goat cheese in a mountain region of Austria.Crossref | GoogleScholarGoogle Scholar |
[8] Brockmann, S.O. et al. (2018) A cluster of two human cases of tick-borne encephalitis (TBE) transmitted by unpasteurized goat milk and cheese in Germany, May 2016. Euro. Surveill. 23, pii=17-00336.
| A cluster of two human cases of tick-borne encephalitis (TBE) transmitted by unpasteurized goat milk and cheese in Germany, May 2016.Crossref | GoogleScholarGoogle Scholar |
[9] Kuivanen, S. et al. (2018) Fatal tick-borne encephalitis virus infections caused by Siberian and European subtypes, Finland, 2015. Emerg. Infect. Dis. 24, 946–948.
| Fatal tick-borne encephalitis virus infections caused by Siberian and European subtypes, Finland, 2015.Crossref | GoogleScholarGoogle Scholar |
[10] Yoshii, K. et al. (2017) Tick-borne encephalitis in Japan, Republic of Korea and China. Emerg. Microbes Infect. 6, e82.
| Tick-borne encephalitis in Japan, Republic of Korea and China.Crossref | GoogleScholarGoogle Scholar |
[11] Taba, P. et al. (2017) EAN consensus review on prevention, diagnosis and management of tick-borne encephalitis. Eur. J. Neurol. 24, 1214-e61.
| EAN consensus review on prevention, diagnosis and management of tick-borne encephalitis.Crossref | GoogleScholarGoogle Scholar |
[12] Varlacher, J.F. et al. (2015) Tick-borne encephalitis. Rev. Sci. Tech. 34, 453–466.
| Tick-borne encephalitis.Crossref | GoogleScholarGoogle Scholar |
[13] Dobler, G. et al. (1997) Cross reactions of patients with acute dengue fever to tick-borne encephalitis. Wien. Med. Wochenschr. 147, 463–464.
[14] Lehrer, A.T. and Holbrook, M.R. (2011) Tick-borne encephalitis vaccines. J. Bioterror. Biodef. 2011, .
| Tick-borne encephalitis vaccines.Crossref | GoogleScholarGoogle Scholar |
[15] WHO (2011) Vaccines against tick-borne encephalitis: WHO position paper – recommendations. Vaccine 29, 8769–8770.
| Vaccines against tick-borne encephalitis: WHO position paper – recommendations.Crossref | GoogleScholarGoogle Scholar |
[16] Süss, J. (2011) Tick-borne encephalitis 2010: epidemiology, risk areas, and virus strains in Europe and Asia-an overview. Ticks Tick Borne Dis. 2, 2–15.
| Tick-borne encephalitis 2010: epidemiology, risk areas, and virus strains in Europe and Asia-an overview.Crossref | GoogleScholarGoogle Scholar |
[17] ECDC Technical Report (2012) Epidemiological situation of tick-borne encephalitis in the European Union and European Free Trade Association countries.
[18] Steffen, R. (2016) Epidemiology of tick-borne encephalitis (TBE) in international travellers to Western Europe and conclusions on vaccination recommendations. J. Travel Med. 23, taw018.
| Epidemiology of tick-borne encephalitis (TBE) in international travellers to Western Europe and conclusions on vaccination recommendations.Crossref | GoogleScholarGoogle Scholar |
[19] Meltzer, E. et al. (2017) Travel-related tick-borne encephalitis, Israel, 2006–2014. Emerg. Infect. Dis. 23, 119–121.
| Travel-related tick-borne encephalitis, Israel, 2006–2014.Crossref | GoogleScholarGoogle Scholar |
[20] Reusken, C. et al. (2011) Case report: tick-borne encephalitis in two Dutch travellers returning from Austria, Netherlands, July and August 2011. Euro Surveill. 16, 20003.
[21] CDC (2010) Tick-borne encephalitis among US travelers to Europe and Asia – 2000–2009. MMWR Morb. Mortal. Wkly. Rep. 59, 335–338.
[22] Chaudhuri, A. and Ruzek, D. (2013) First documented case of imported tick-borne encephalitis in Australia. Intern. Med. J. 43, 93–96.
| First documented case of imported tick-borne encephalitis in Australia.Crossref | GoogleScholarGoogle Scholar |
